The Power Of NMR in Biosimilars Comparability Assessment
In the this article we discuss evidence that shows that NMR spectroscopy is far superior to other established methods for biosimilar’s comparability assessment.
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WAC™ Fragment screening technology: Principles & Advantages
In this article, we discuss weak affinity chromatography (WAC™), the proprietary fragment screening technique jointly owned by SARomics Biostructures and Red Glead Discovery.
Room-Temperature Crystallography In Drug Design
In this post we want to bring to the attention of our readers the revival of room-temperature (RT) protein crystallography using synchrotron radiation and its potential applications in structure-based drug design to study of functionally-important conformations.
Structural Biology of Therapeutic Monoclonal Antibodies
X-ray crystallography has provided detailed information on the three-dimensional structure of monoclonal antibodies, revealing domain organization, dynamics, and the structure of the paratope and epitope regions. Image above was generated by Affinity Designer 2, https://geblerconsulting.com/
Fragment Screening & Hit Identification: Which Library to Choose?
In this third post on structural biology and structure-based drug design we discuss fragment libraries and fragment-based lead discovery