DNA-Encoded Library Screening For Drug Discovery
SARomics Biostructures AB and Vipergen ApS partner to offer hit and lead identification services based on Vipergen’s unique DNA-encoded library (DEL) screening technology.
X-ray crystallography
The Power Of NMR in Biosimilars Comparability Assessment
In the this article we discuss evidence that shows that NMR spectroscopy is far superior to other established methods for biosimilar’s comparability assessment.
2023 – More Structural Biology & Drug Discovery
In this article, we will discuss some significant publications and company activities in 2023. The publications showcase our expertise in the three main areas of our services: X-ray crystallography, NMR spectroscopy, and integrated drug discovery.
Room-Temperature Crystallography In Drug Design
In this post we want to bring to the attention of our readers the revival of room-temperature (RT) protein crystallography using synchrotron radiation and its potential applications in structure-based drug design to study of functionally-important conformations.
Biosimilars: Structure Comparability Analysis
In the second part of our article series on antibody therapeutics, we discuss biosimilars and their structure comparability analysis.
Structural Biology of Therapeutic Monoclonal Antibodies
X-ray crystallography has provided detailed information on the three-dimensional structure of monoclonal antibodies, revealing domain organization, dynamics, and the structure of the paratope and epitope regions. Image above was generated by Affinity Designer 2, https://geblerconsulting.com/
The Dusquetide Saga – a Structural Blast From the Past!
A pleasant surprise! A paper describing the interaction of the therapeutic peptide dusquetide with the ZZ domain of the autophagic receptor p62 was published around 12 years after the structure was solved!
Choosing A Drug Design Strategy
Which strategy to choose when planning a drug discovery project? Maybe structure-based design, ligand-based design, or de novo design? These questions are discussed in our series on structure-based drug design in this second post.
Structural Biology & Drug Discovery Services Company
Applying structural biology methods requires many different skills and experience. A structural biology services company technology platform brings together all experimental methods and people with the skills required to run a structure-based drug discovery project.
EU-Funded Research Projects with SARomics
Since our first trip into the realm of EU projects with the KINOMED project, we have engaged in 7 different…