FastLane™ Structure Libraries

X-ray crystallography services at SARomics Biostructures are run at our cutting-edge, high-throughput pipeline anchored by our FastLane™ Premium and FastLane™ Standard libraries.

X-ray crystallography services - FastLane premium library

FastLane™ Premium Structures

Library of verified drug targets that have already been expressed, purified, and crystallized at the company (off-the-shelf structures). Purified proteins are available for the immediate start of a project.

FastLane™ standard

Library of verified drug targets for which expression plasmids and protocols for expression, purification, and crystallization are available at the company.

FastLane™ Structures Libraries of Proteins and constructs

Our FastLane™ Premium and FastLane™ Standard libraries boast 500+ verified drug targets ready to be directly crystallized with your chosen ligand (FastLane™ Premium) or expressed, purified, and crystallized according to verified protocols (FastLane™ Standard) within a few weeks.

Please find below the details of our FastLane™ Premium and FastLane™ Standard libraries of off-the-shelf drug-target proteins. To explore the details of our X-ray crystallography services, please visit our services page and methods and technologies knowledge center.

the FastLane™ Premium Library

The FastLane™ Premium library currently contains drug-target proteins ready for co-crystallization with ligands. The library includes an extensive collection of kinases, phosphatases, proteases, epigenetic factors, and other drug targets. Using our high-throughput X-ray crystallography services pipeline, the turnaround time for structure determination for these proteins is between 2 to 8 weeks (depending on the protein).

Gene	Protein	Function/Process	UniProt ID
BTK	Tyrosine-protein kinase BTK	Kinase	Q06187
CDK2	Cyclin-dependent kinase 2	Kinase	P24941
CDK5	Cyclin-dependent kinase 5	Kinase	Q00535
CDK7	Cyclin-dependent kinase 7	Kinase	P50613
CK2	Casein kinase II subunit alpha	Kinase	P68400
CLK3	Dual specificity protein kinase CLK3	Kinase	P49761
DAPK3	Death-associated protein kinase 3	Kinase	O43293
DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Kinase	Q13627
EPHA7	Ephrin type-A receptor 7	Kinase	Q15375
FGFR1	Fibroblast growth factor receptor 1	Kinase	P11362
FRK	Non-receptor tyrosine-protein kinase	Kinase	P42685
ITK	Tyrosine-protein kinase ITK/TSK	Kinase	Q08881
KIT	Tyrosine-protein kinase, Mast/stem cell growth factor receptor Kit	Kinase	P10721
LATS2	Serine/threonine-protein kinase LATS2	Kinase	Q9NRM7
MAP2K4	Dual specificity mitogen-activated protein kinase kinase 4	Kinase	P45985
NDR2	Serine/threonine-protein kinase 38-like	Kinase	Q9Y2H1
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Kinase	Q16875
PIM1	Serine/threonine-protein kinase pim-1	Kinase	P11309
PIM3	Serine/threonine-protein kinase pim-3	Kinase	Q86V86
PIP4K2A	PIP5K2A or Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Kinase	P48426
PLK1	Serine/threonine-protein kinase PLK1	Kinase	P53350
PLK4	Serine/threonine-protein kinase PLK4	Kinase	O00444
RET	Proto-oncogene tyrosine-protein kinase receptor Ret	Kinase	P07949
RIPK3	Receptor-interacting serine/threonine-protein kinase 3 (mouse)	Kinase	Q9QZL0
ROCK2	Rho-associated protein kinase 2	Kinase	O75116
RSK1	RPS6KA1 Ribosomal protein S6 kinase alpha-1	Kinase	Q15418
RSK2	Ribosomal protein S6 kinase	Kinase	Q15418
SRPK1	SRSF protein kinase 1	Kinase	Q96SB4
STK10	LOK or Serine/threonine-protein kinase 10	Kinase	O94804
STK17A	DRAK1 or Serine/threonine-protein kinase 17A	Kinase	Q9UEE5
STK17B	DRAK2 or Serine/threonine-protein kinase 17B	Kinase	O94768
TYK2	Non-receptor tyrosine-protein kinase TYK2	Kinase	P29597
Vps34	PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3	Kinase	Q8NEB9
VRK1	Serine/threonine-protein kinase VRK1	Kinase	Q99986
VRK2	Serine/threonine-protein kinase VRK2	Kinase	Q8BN21
ATAD2A	ATPase family AAA domain-containing protein 2	Epigenetic targets	Q6PL18
ATAD2B	ATPase family AAA domain-containing protein 2B	Epigenetic targets	Q9ULI0
JMJD2C	KDM4C Lysine-specific demethylase 4C	Epigenetic targets	Q9H3R0
SMARCA2B	Probable global transcription activator SNF2L2	Epigenetic targets	P51531
CASP1	Caspase-1	Peptidase	P29466
Cathepsin C	CPPI, Dipeptidyl peptidase 1	Peptidase	P53634
DPP4	Dipeptidyl peptidase 4	Peptidase	P27487
Thrombin	F2, Human alpha thrombin	Peptidase	P00734
PTPN1	PTP1B, Tyrosine-protein phosphatase non-receptor type 1	Phosphatase	P18031
SHP2	PTPN11, Tyrosine-protein phosphatase non-receptor type 11	Phosphatase	Q06124
USP21	UBP21, Ubiquitin carboxyl-terminal hydrolase 21	Hydrolase	Q9UK80
USP7	UBP7, Ubiquitin carboxyl-terminal hydrolase 7	Hydrolase	Q93009
USP8	UBP8, Ubiquitin carboxyl-terminal hydrolase 8	Hydrolase	P40818
ALB	Human albumin, HSA	Transporter	P02768
BCAT2	Branched-chain-amino-acid aminotransferase, mitochondrial	amino acid metabolic enzymes	O15382
BCL2A1	BFL1, Bcl-2-related protein A1	Hemopoietic-specific early response protein	Q16548
BSSL	Bile salt-activated lipase	Lipase/esterase	P19835
CD11b	Human Integrin alpha M	Integrin	P11215
CD28	T-cell-specific surface glycoprotein CD28	CD28	P10747
CD47	Leukocyte surface antigen CD47	Integrin-associated protein (IAP)	Q08722
CD137	TNFRSF9, Tumor necrosis factor receptor superfamily member 9	T-cell antigen 4-1BB homolog	Q07011
CGAS	elF4E, Eukaryotic translation initiation factor 4E	cGAMP synthase	Q8N884
DHODH	Dihydroorotate dehydrogenase	Pyrimidine metabolism	Q02127
EIF4E	Eukaryotic translation initiation factor 4E	Protein biosynthesis	P06730
EPAS1	Hif2alpha, Endothelial PAS domain-containing protein 1	Activator	Q99814
Gal-1	LGALS1, recombinant Galectin-1	Lectin	P09382
Gal-3C	LGALS3, recombinant Galectin-3 C-terminal carbohydrate binding domain	Galactose-specific lectin 3	P17931
Gal-8N	LGALS8, recombinant Galectin 8 N-terminal carbohydrate binding domain	Beta-galactoside-binding lectin	O00214
Gal-9N	LGALS9, recombinant Galectin 9 N-terminal carbohydrate binding domain	Lectin	O00182
Gal-9C	LGALS9, recombinant Galectin 9 C-terminal carbohydrate binding domain	Lectin	O00182
GART	Trifunctional purine biosynthetic protein adenosine-3 (a.a. 808-1010)	Purine metabolism	P22102
GMPR2	GMP reductase 2	Oxidoreductase	Q9P2T1
HER2	Receptor protein-tyrosine kinase extracellular domain	Extracellular domain	Q9UK79
HSP90	Heat shock protein HSP 90-alpha	Chaperone	P07900
IL-4	Recombinant Interleukin-4	Cytokine	P05112
IL-13	Recombinant Interleukin-13	Cytokine	P35225
IL-17A	Recombinant Interleukin-17A	Cytokine	Q16552
IL-23	IL-23A, Interleukin-23, subunits alpha and beta	Cytokine	Q9NPF7
K-Ras-cys mut	Recombinant GTPase K-Ras	GTPase	P01116
K-RasG12C	Recombinant GTPase K-Ras G12C	GTPase	P01116
K-RasG12D	Recombinant GTPase K-Ras G12D	GTPase	P01116
K-RasG12V	Recombinant GTPase K-Ras G12C	GTPase	P01116
LDHA	LDHA, L-lactate dehydrogenase A chain (rabbit)	Fermentation	P13491
NRP1	Neuropilin-1	Cell-surface receptor/signaling	O14786
PD-1	PDCD1, Programmed cell death 1	Cell-surface receptor	Q15116
PD-L1	PDL1, Programmed cell death 1 ligand 1	Cell-surface receptor	B5XDX7
PDE4D	cAMP-specific 3′,5′-cyclic phosphodiesterase 4D	Hydrolase	Q08499
PPARgamma	Peroxisome proliferator-activated receptor gamma	Nuclear receptor	P37231
PSD95	DLG4, Disks large homolog 4	Postsynaptic density protein 95	P78352
RORgamma	Nuclear receptor ROR-gamma	Nuclear receptor	P51449
S100A12	Protein S100-A12	Calcium-, zinc- and copper-binding	P80511
S100A4	Mts1 or Protein S100-A4	Calcium-binding	P26447
S100A9	MRP14, Protein S100-A9	Calcium- and zinc-binding protein	P06702
TNF-alpha	Tumor necrosis factor	Cytokine	P01375
TL1A	Tumor necrosis factor ligand superfamily member 15	Cytokine	O95150
TUBA1A	Tubulin alpha-1A (pig)	Hydrolase	P02550
Ubiquitin	Ubiquitin-60S ribosomal protein L40	Protein synthesis	P62987
blaC	Beta-lactamase (M. tuberculosis)	Hydrolase	P9WKD3
gyrB	DNA gyrase subunit B (S. aureus)	Type II topoisomerase, DNA binding	Q6GD85
Snf	LeuT, Na(+):neurotransmitter symporter, Snf family (Aquifex aeolicus VF5)	Transporter	O67854
SARS CoV-2 RBD	Spike glycoprotein receptor-binding domain (SARS-CoV-2)	Attaches the virion to the cell membrane	P0DTC2
SARS CoV-2 RBD beta	Spike glycoprotein receptor-binding domain, B.1.351 variant (SARS-CoV-2)	Attaches the virion to the cell membrane	P0DTC2
SARS CoV-2 RBD omicron	Spike glycoprotein receptor-binding domain, XBB.1.5 variant (SARS-CoV-2)	Attaches the virion to the cell membrane	P0DTC2

contact SARomics Biostructures to discuss your structural biology project

SARomics Biostructure’s X-ray crystallography services are leveraged by our location close to the MAX IV Laboratory in Lund, one of the most advanced synchrotron radiation facilities in the world.

the FastLane™ Standard Library

The FastLane™ Standard library currently contains around 500 constructs of drug target proteins ready for expression, purification, crystallization, and X-ray crystallographic structure determination according to verified protocols. The library includes a large number of protein kinases, phosphatases, epigenetic factors, and many other drug targets. Using our high-throughput protein X-ray crystallography pipeline, the turnaround time for structure determination for these proteins is between 6 to 12 weeks (depending on the protein).

How to search the table
The table can be serched by individual protein name or a whole protein family. For example, entering “kinase” in the search field will return a list of all kinases in the library. The protein families with the largest number of entries in the library may be found using the search terms: amino acid metabolic enzyme, ATPase, bromodomain, BTB-Kelch, E3-Ligase, epigenetic targets, G-protein regulator, GTPase, hydrolase, linker-PDZ, lipid signaling, nucleotide metabolism, oxidoreductase, PARP, phosphatase, phosphoinositide dependent signaling, transferase.

Gene	Protein name	UniProt ID	Sequence range	Function/Process	PDB ID
AHCYL1	S-adenosylhomocysteine hydrolase-like protein 1	O43865	89-530	amino acid metabolic enzymes	3MTG
AHCYL2	Adenosylhomocysteinase 3, NAD binding domain	Q96HN2	175-607	amino acid metabolic enzymes	3GVP
ASS1	Argininosuccinate synthase	P00966	1-412	amino acid metabolic enzymes	2NZ2
CSAD	Cysteine sulfinic acid decarboxylase	Q9Y600	1-493	amino acid metabolic enzymes	2JIS
CTH	Cystathionine gamma-lyase	P32929	1-402	amino acid metabolic enzymes	2NMP/3COG
GLUL	Glutamine synthetase	P15104	5-365	amino acid metabolic enzymes	2OJW
GPT2	Alanine aminotransferase 2	Q8TD30	49-523	amino acid metabolic enzymes	3IHJ
MPST	3-mercaptopyruvate sulfurtransferase	P25325	11-289	amino acid metabolic enzymes	3OLH
PCYT2	Ethanolamine-phosphate cytidylyltransferase	Q99447	18-356	amino acid metabolic enzymes	3ELB
PSAT1	Phosphoserine aminotransferase	Q9Y617	17-370	amino acid metabolic enzymes
SCLY	Selenocysteine lyase	Q96I15	8-445	amino acid metabolic enzymes	2HDY/3GZC/3GZD
TAT	Tyrosine aminotransferase	P17735	41-444	amino acid metabolic enzymes	3DYD
GFPT1	Glutamine–fructose-6-phosphate aminotransferase [isomerizing] 1, isomerase domain	Q06210	332-649	Aminotransferas	2V4M
BIRC3	Baculoviral IAP repeat-containing protein 3, BIR domain	Q13489	242-337	Apoptosis-Inflammation Domains	2UVL
NAIP	Baculoviral IAP repeat-containing protein 1, BIR2 domain	Q13075	139-244	Apoptosis-Inflammation Domains	2VM5
ALOX12	Polyunsaturated fatty acid lipoxygenase	P18054	172-663	Arachidonic acid metabolism	3D3L
PTGDS	Prostaglandin-H2 D-isomerase	P41222	23-190	Arachidonic acid metabolism	2WWP
FIGNL1	Fidgetin-like protein 1	Q6PIW4	341-674	ATPases – AAA	3D8B
NVL	Nuclear valosin-containing protein-like	O15381	573-845	ATPases – AAA	2X8A
SPG7	Paraplegin	Q9UQ90	305-565	ATPases – AAA	2QZ4
DDX10	Probable ATP-dependent RNA helicase	Q13206	47-280	ATPases – DExD-DExH RNA helicases	2PL3
DDX18	ATP-dependent RNA helicase	Q9NVP1	149-387	ATPases – DExD-DExH RNA helicases	3LY5
DDX19B	ATP-dependent RNA helicase	Q9UMR2	54-475	ATPases – DExD-DExH RNA helicases	3EWS/3G0H
DDX20	Probable ATP-dependent RNA helicase	Q9UHI6	41-268	ATPases – DExD-DExH RNA helicases	2OXC/3B7G
DDX25	ATP-dependent RNA helicase	Q9UHL0	307-479	ATPases – DExD-DExH RNA helicases	2G2J/2RB4
DDX3X	ATP-dependent RNA helicase	O00571	168-352	ATPases – DExD-DExH RNA helicases	2I4I
DDX41	Probable ATP-dependent RNA helicase DDX41	Q9UJV9	402-569	ATPases – DExD-DExH RNA helicases	2P6N
DDX47	Probable ATP-dependent RNA helicase	Q9H0S4	5-230	ATPases – DExD-DExH RNA helicases	3BER
DDX5	Probable ATP-dependent RNA helicase	P17844	68-307	ATPases – DExD-DExH RNA helicases	3FE2
DDX52	Probable ATP-dependent RNA helicase	Q9Y2R4	139-381	ATPases – DExD-DExH RNA helicases	3DKP
DDX53	Probable ATP-dependent RNA helicase	Q86TM3	204-430	ATPases – DExD-DExH RNA helicases	3IUY
DHX9	ATP-dependent RNA helicase A	Q08211	329-563	ATPases – DExD-DExH RNA helicases	3LLM
EIF4A1	Eukaryotic initiation factor 4A-I	P60842	20-238	ATPases – DExD-DExH RNA helicases	2G9N
IFIH1	Interferon-induced helicase C domain-containing protein 1	Q9BYX4	277-490	ATPases – DExD-DExH RNA helicases	3B6E
HSPA1A	Heat shock 70 kDa protein 1A	P0DMV8	1-387	ATPases – Hsp70	3JXU
HSPA1L	Heat shock 70 kDa protein 1-like	P34931	1-386	ATPases – Hsp70	3GDQ
HSPA2	Heat shock-related 70 kDa protein 2	P54652	6-386	ATPases – Hsp70	3I33
HSPA5	Endoplasmic reticulum chaperone BiP	P11021	26-410	ATPases – Hsp70	3IUC
HSPA6	Heat shock 70 kDa protein 6	P17066	6-385	ATPases – Hsp70	3FE1
HSPA9	Stress-70 protein, mitochondrial	P38646	439-597	ATPases – Hsp70	3N8E
BRDT	Bromodomain testis-specific protein	Q58F21	21-137	Bromodomain	2RFJ
CECR2	Chromatin remodeling regulator CECR2, bromodomain	Q9BXF3	424-538	Bromodomain	3NXB
CREBBP	CREB-binding protein, bromodomain	Q92793	1081-1197	Bromodomain	3P1D
EP300	Histone acetyltransferase p300, bromodomain	Q09472	1040-1161	Bromodomain	3I3J
KAT2A	Histone acetyltransferase KAT2A, bromodomain	Q92830	729-837	Bromodomain	3D7C
KAT2B	Histone acetyltransferase KAT2B, bromodomain	Q92831	715-831	Bromodomain	3GG3
PBRM1	Protein polybromo-1, bromodomain	Q86U86	43-156	Bromodomain	3G0J
PBRM1	Protein polybromo-1, bromodomain	Q86U86	178-291	Bromodomain	3HMF
PBRM1	Protein polybromo-1, bromodomain	Q86U86	388-494	Bromodomain	3IU5
PBRM1	Protein polybromo-1, bromodomain	Q86U86	645-766	Bromodomain	3IU6
PBRM1	Protein polybromo-1, bromodomain	Q86U86	773-917	Bromodomain	3K2J
PHIP	PH-interacting protein, bromodomain 2	Q8WWQ0	1302-1434	Bromodomain	3MB3
TAF1L	Transcription initiation factor TFIID subunit 1-like, bromodomain	Q8IZX4	1523-1654	Bromodomain	3HMH
BACH1	Transcription regulator protein BACH1, BTB domain	O14867	7-128	BTB-Kelch	2IHC
BTBD6	BTB/POZ domain-containing protein 6	Q96KE9	129-236	BTB-Kelch	2VKP
GAN	Gigaxonin, BTB domain	Q9H2C0	6-126	BTB-Kelch	2PPI
KLHL11	Kelch-like protein 11	Q9NVR0	67-340	BTB-Kelch	3I3N
KLHL12	Kelch-like protein 12	Q53G59	267-567	BTB-Kelch	2VPJ
KLHL2	Kelch-like protein 2	O95198	294-591	BTB-Kelch	2XN4
KLHL7	Kelch-like protein 7	Q8IXQ5	283-586	BTB-Kelch	3II7
MYNN	Myoneurin, BTB domain	Q9NPC7	4-117	BTB-Kelch	2VPK
ZBTB33	Transcriptional regulator Kaiso, BTB domain	Q86T24	1-116	BTB-Kelch	3FKC
ZBTB48	Telomere zinc finger-associated protein, BTB domain	P10074	4-120	BTB-Kelch	3B84
RADIL	Ras-associating and dilute domain-containing protein, Ras association domain	Q96JH8	51-193	Cell-type specific expression – endothelial cell	3EC8
GUCY1B1	Guanylate cyclase 1, soluble, beta-1	Q02153	408-619	Cyclase-Nucleotide	2WZ1
MACROD1	ADP-ribose glycohydrolase MACROD1, MACRO domain	Q9BQ69	91-325	Deacetyalases	2X47
RECQL	ATP-dependent DNA helicase Q1	P46063	49-616	DEAD-DNA-Helicase	2V1X
ALDH1L1	Cytosolic 10-formyltetrahydrofolate dehydrogenase	O75891	1-307	Dehydrogenases & Reductases – Other DRs	2BW0/2CFI
DPYSL2ﾠﾠﾠ	Dihydropyrimidinase-related protein 2	Q16555	13-490	Dehydrogenases & Reductases – Other DRs	2GSE
DPYSﾠﾠﾠ	Dihydropyrimidinase	Q14117	1-519	Dehydrogenases & Reductases – Other DRs	2VR2
CBLB	E3 ubiquitin-protein ligase CBL-B	Q13191	38-344	E3-Ligase	3PFV
CBLC	E3 ubiquitin-protein ligase CBL-C	Q9ULV8	9-323	E3-Ligase	3OP0
CUL5	Cullin-5	Q9D5V5	1-386	E3-Ligase	2WZK
ERI3	ERI1 exoribonuclease 3	O43414	137-337	Endo/Exo Nucleases	2XRI
EXOG	Nuclease EXOG, mitochondrial	Q9Y2C4	42-368	Endo/Exo Nucleases	4A1N
ASH1L	Histone-lysine N-methyltransferase ASH1L, bromodomain	Q9NR48	2438-2561	Epigenetic targets: Bromodomains	3MQM
BAZ2B	Bromodomain adjacent to zinc finger domain protein 2B	Q9UIF8	2054-2168	Epigenetic targets: Bromodomains	3G0L
BPTF	Nucleosome-remodeling factor subunit BPTF, bromodomain	Q12830	2914-3037	Epigenetic targets: Bromodomains
BRD1	Bromodomain-containing protein 1	O95696	556-688	Epigenetic targets: Bromodomains	3RCW
BRD9	Bromodomain-containing protein 9	O95696	134-239	Epigenetic targets: Bromodomains	3HME
BRWD1	Bromodomain and WD repeat-containing protein 1, bromodomain 2	Q9NSI6	1310-1430 Bromodomain 2	Epigenetic targets: Bromodomains	3Q2E
MINA	Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA	Q8IUF8	26-465	Epigenetic targets: Demethylases	2XDV
RGS1	Regulator of G-protein signaling 1	Q08116	63-205	G-protein-Regulator	2BV1
RGS10	Regulator of G-protein signaling 10 (isoform b)	O43665	30-165	G-protein-Regulator	2I59
RGS14	Regulator of G-protein signaling 14	O43566	56-207	G-protein-Regulator	2JNU
RGS16	Regulator of G-protein signaling 16	O15492	53-190	G-protein-Regulator	2BT2
RGS17	Regulator of G-protein signaling 17	Q9UGC6	72-206	G-protein-Regulator	1ZV4
RGS18	Regulator of G-protein signaling 18	Q9NS28	75-223	G-protein-Regulator	2OWI
RGS2	Regulator of G-protein signaling 2	P41220	71-203	G-protein-Regulator	2AF0
RGS3	Regulator of G-protein signaling 3 (isoform 1), PDZ domain	P49796	299-384	G-protein-Regulator	2F5Y
RGS6	Regulator of G-protein signaling 6	P49758	325-470	G-protein-Regulator	2ES0
RGS7	Regulator of G-protein signaling 7	P49802	320-463	G-protein-Regulator	2A72
RGS8	Regulator of G-protein signaling 8	P57771	42-173	G-protein-Regulator	2IHD
ARHGAP15	Rho GTPase-activating protein 15	Q53QZ3	262-473	GTPase-GAP	3BYI
RACGAP1	Rac GTPase-activating protein 1	Q9H0H5	348-546	GTPase-GAP	2OVJ
AGAP2	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, GTPase like domain	Q99490	402-577	GTPase-RAS	2IWR
DIRAS1	GTP-binding protein Di-Ras1	O95057	1-198	GTPase-RAS	2GF0
DIRAS2	GTP-binding protein Di-Ras2	Q96HU8	5-176	GTPase-RAS	2ERX
GEM	GTP-binding protein GEM	P55040	62-249	GTPase-RAS	2G3Y
REM1	GTP-binding protein REM 1	O75628	79-251	GTPase-RAS	2NZJ
RERG	Ras-related and estrogen-regulated growth inhibitor	Q96A58	1-174	GTPase-RAS	2ATV
RRAD	GTP-binding protein RAD	P55042	87-260	GTPase-RAS	2GJS
RRAS	Ras-related protein R-Ras	P10301	23-201	GTPase-RAS	2FN4
RRAS2	Ras-related protein R-Ras2	P62070	12-181	GTPase-RAS	2ERY
RAC3	Ras-related C3 botulinum toxin substrate 3	P60763	1-192	GTPase-RHO	2C2H
RHOB	Rho-related GTP-binding protein RhoB	P62745	4-184	GTPase-RHO	2FV8
RHOD	Rho-related GTP-binding protein RhoD	O00212	7-197	GTPase-RHO	2J1L
RHOU	Rho-related GTP-binding protein RhoU	Q7L0Q8	32-230	GTPase-RHO	2Q3H
RND1	Rho-related GTP-binding protein Rho6	Q92730	5-200	GTPase-RHO	2CLS
ADA	Adenosine deaminase	P00813	5-363	Hydrolase-Other	3IAR
ECH1	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial	Q13011	39-49,50-322	Hydrolase-Other	2VRE
ECHDC3	Enoyl-CoA hydratase domain-containing protein 3, mitochondrial	Q96DC8	37-300	Hydrolase-Other	2VX2
ECHS1	Enoyl-CoA hydratase, mitochondrial	P30084	28-290	Hydrolase-Other	2HW5
ERAP1	Endoplasmic reticulum aminopeptidase 1	Q9NZ08	1-505	Hydrolase-Other	2XDT
FH	Fumarate hydratase, mitochondrial	P07954	44-510	Hydrolase-Other	3E04
HDHD2	Haloacid dehalogenase-like hydrolase domaing-containing 2	Q9H0R4	1-259	Hydrolase-Other	3HLT
HDHD3	Haloacid dehalogenase-like hydrolase domain-containing 3	Q9BSH5	8-247	Hydrolase-Other	3K1Z
HIBCH	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	Q6NVY1	32-386	Hydrolase-Other	3BPT
MDP1	Magnesium-dependent phosphatase 1	Q86V88	1-165	Hydrolase-Other	2WM8
PTS	6-pyruvoyltetrahydropterin synthase	Q03393	7-145	Hydrolase-Other	3I2B
PUDP	Pseudouridine-5′-phosphatase	Q08623	1-228	Hydrolase-Other	3L5K
ECI2	Enoyl-CoA delta isomerase 2	O75521	137-394	Isomerase	2F6Q
MMUT	Methylmalonyl-CoA mutase, mitochondrial	P22033	12-750	Isomerase	3BIC
AKT3	RAC-gamma serine/threonine-protein kinase	Q9Y243	1-118	Kinase-AGC	2X18
DMPK	Myotonin-protein kinase	Q09013	10-420	Kinase-AGC	2VD5
MAST1	Microtubule associated serine/threonine kinase 1, PDZ domain	Q9Y2H9	965-1057	Kinase-AGC	3PS4
MAST3	Microtubule associated serine/threonine kinase 3, PDZdomain	O60307	948-1040	Kinase-AGC	3KHF
MAST4	Microtubule-associated serine/threonine-protein kinase 4 , PDZ domain	O15021	1140-1231	Kinase-AGC	2W7R
PRKCG	Protein kinase C gamma type, C2 domain	P05129	154-295	Kinase-AGC	2UZP
RPS6KA1	Ribosomal protein S6 kinase alpha-1	Q15418	404-719	Kinase-AGC	2WNT
CAMK1D	Calcium/calmodulin-dependent protein kinase type 1D	Q8IU85	1-333	Kinase-CAMK	2JC6
CAMK1G	Calcium/calmodulin-dependent protein kinase type 1G	Q96NX5	18-316	Kinase-CAMK	2JAM
CAMK2A	Calcium/calmodulin-dependent protein kinase type II subunit alpha	Q9UQM7	13-302	Kinase-CAMK	2VZ6
CAMK2B	Calcium/calmodulin-dependent protein kinase type II subunit beta	Q13554	11-303	Kinase-CAMK	3BHH
CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	Q13557	11-309	Kinase-CAMK	2VN9
CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	Q13557	334-475	Kinase-CAMK	2W2C
CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Q13555	5-315	Kinase-CAMK	2V7O
CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Q13555	425-558	Kinase-CAMK	2UX0
CAMK4	Calcium/calmodulin-dependent protein kinase type IV	Q16566	15-340	Kinase-CAMK	2W4O
MYLK4	Myosin light chain kinase family, member 4	Q86YV6	40-388	Kinase-CAMK	2X4F
PHKG2	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	P15735	6-293	Kinase-CAMK	2Y7J
PIM2	Serine/threonine-protein kinase	Q9P1W9	1-311	Kinase-CAMK	2IWI
CSNK1G1	Casein kinase I isoform gamma-1	P78368	45-352	Kinase-CK1	2CMW
CSNK1G2	Casein kinase I isoform gamma-2	Q9HCP0	43-353	Kinase-CK1	2C47
CSNK1G3	Casein kinase I isoform gamma-3	Q9Y6M4	35-362	Kinase-CK1	2IZR
VRK1	Serine/threonine-protein kinase VRK1, protein kinase domain	Q99986	3-364	Kinase-CK1	3OP5
VRK2	Serine/threonine-protein kinase VRK2, protein kinase domain	Q86Y07	14-335	Kinase-CK1	2V62
VRK3	Serine/threonine-protein kinase VRK3, protein kinase domain	Q8IV63	138-474	Kinase-CK1	2JII
CLK1	Dual specificity protein kinase CLK1	P49759	148-484	Kinase-CMGC	1Z57
CLK2	Dual specificity protein kinase CLK2	P49760	135-496	Kinase-CMGC	3NR9
DYRK2	Dual specificity tyrosine-phosphorylation-regulated kinase 2	Q92630	146-552	Kinase-CMGC	3K2L
MAPK11	Mitogen-activated protein kinase 11 (p38b)	Q15759	5-350	Kinase-CMGC	3GP0
MAPK6	Mitogen-activated protein kinase 6	Q16659	9-327	Kinase-CMGC	2I6L
PCTK1	Cyclin-dependent kinase 16	Q00536	163-478	Kinase-CMGC	3MTL
SRPK2	SFRS protein kinase 2	P78362	50-688	Kinase-CMGC	2X7G
GAK	Cyclin-G-associated kinase	O14976	12-347	Kinase-Other	3LL6
PTK2B	Protein-tyrosine kinase 2-beta	Q14289	414-692	Kinase-Other	3CC6
STK16	Serine/threonine protein kinase 16	O75716	13-305	Kinase-Other	2BUJ
TTK	Dual specificity protein kinase TTK	P33981	519-808	Kinase-Other	3CEK
ITPK1	Inositol-tetrakisphosphate 1-kinase	Q13572	1-327	Kinase-PIK	2ODT
ITPKC	Inositol-trisphosphate 3-kinase C	Q96DU7	425-683	Kinase-PIK	2A98
PIK3C2G	Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma, PX domain	O75747	1198-1307	Kinase-PIK	2WWE
PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3	Q8NEB9	282-879	Kinase-PIK	3IHY
PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3	Q8NEB9	268-879	Kinase-PIK	3LS8
PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta	O00459	108-298	Kinase-PIK	2XS6
PIP5K2C	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Q8TBX8	32-421	Kinase-PIK	2GK9
MAP2K6	Dual specificity mitogen-activated protein kinase kinase 6	P52564	47-334	Kinase-STE	3FME
MAP3K3	Mitogen-activated protein kinase kinase kinase 3 (isoform 2) PB1 domain	Q99759	27-124	Kinase-STE	2C60
MAP3K5	Mitogen-activated protein kinase kinase kinase 5 (MAPK/ERK kinase kinase 5)	Q99683	659-951	Kinase-STE	2CLQ
PAK4	Serine/threonine-protein kinase PAK 4	O96013	291-591	Kinase-STE	2Q0N
PAK5	Serine/threonine-protein kinase PAK 5	Q9P286	425-719	Kinase-STE	2F57
PAK6	Serine/threonine-protein kinase PAK 6	Q9NQU5	383-681	Kinase-STE	2C30
SLK	STE20-like serine/threonine-protein kinase	Q9H2G2	12-15,16-320	Kinase-STE	2UV2
STK25	Serine/threonine-protein kinase 25	O00506	1-293	Kinase-STE	2XIK
STK26	Serine/threonine-protein kinase 26	Q9P289	1-300	Kinase-STE	3GGF
TNIK	TRAF2 and NCK interacting protein kinase	Q9UKE5	1-325	Kinase-STE	2X7F
ABL2	Tyrosine-protein kinase ABL2	P42684	279-546	Kinase-TK	3GVU
FES	Tyrosine-protein kinase Fes/Fps	P07332	448-822	Kinase-TK	3BKB
FLT1	Vascular endothelial growth factor receptor 1	P17948	801-1158	Kinase-TK and PARP domain?	3HNG
ACVR1	Activin receptor type-1	Q04771	201-499	Kinase-TKL	3MTF
ACVR2A	Activin receptor type-2A	P27037	191-488	Kinase-TKL	3SOC
ACVRL1	Serine/threonine-protein kinase receptor R3	P37023	195-497	Kinase-TKL	3MY0
LIMK1	LIM domain kinase 1 (isoform 1), kinase domain	P53667	330-637	Kinase-TKL	3S95
MAP3K10	Mitogen-activated protein kinase kinase kinase 10, SH3 domains	Q02779	13-78	Kinase-TKL	2RF0
ROR2	Tyrosine-protein kinase transmembrane receptor ROR2	Q01974	463-751	Kinase-Tyr	3ZZW
AK1	Adenylate kinase isoenzyme 1	P00568	1-193	Kinases	2C95
AK2	Adenylate kinase isoenzyme 2, mitochondrial	P54819	1-239	Kinases	2C9Y
AK4	Adenylate kinase isoenzyme 4, mitochondrial	P27144	1-223	Kinases	2BBW
AK5	Adenylate kinase isoenzyme 5	Q9Y6K8	366-562	Kinases	2BWJ
BMPR2	Bone morphogenetic protein receptor type-2	Q13873	189-517	Kinases	3G2F
HASPIN	Serine/threonine-protein kinase haspin	Q8TF76	465-798	Kinases
MPSK1	Serine/threonine-protein kinase 16	O75716	13-305	Kinases
MST4	Serine/threonine-protein kinase	Q9P289	1-300	Kinases
NEK2	Serine/threonine-protein kinase	P51955	1-271	Kinases	2JAV
ACACA	Acetyl-CoA carboxylase 1	Q13085	78-617	Ligase	2YL2
PCCA	Propionyl-Coenzyme A carboxylase, alpha polypeptide precursor	P05165	658-728	Ligase	2JKU
ACSM2A	Acyl-coenzyme A synthetase ACSM2A, mitochondrial	Q08AH3	32-577	Ligase AMP-Binding	3C5E
DLG2	Discs, large homolog 2, second PDZ domain	Q15700	418-513	Linker-PDZ	2HE2
DLG2	Discs, large homolog 2, first PDZ domain	Q15700	190-283	Linker-PDZ	2BYG
DLG3	Discs, large homolog 3 first PDZ domain	Q92796	126-222	Linker-PDZ	2I1N
DLG3	Discs, large homolog 3 second PDZ domain	Q92796	223-314	Linker-PDZ	2FE5
DVL2	Segment polarity protein dishevelled homolog DVL-2, PDZ domain	O14641	261-355	Linker-PDZ	2REY
GIPC2	PDZ domain-containing protein GIPC2	Q8TF65	112-200	Linker-PDZ	3GGE
GRIP1	Glutamate receptor interacting protein 1, 2nd PDZ domain	Q9Y3R0	148-239	Linker-PDZ	2JIL
LNX1	E3 ubiquitin-protein ligase LNX, PDZ domain	Q8TBB1	504-594	Linker-PDZ	3B76
LNX2	Ligand of Numb protein X 2, PDZ domain	Q8N448	336-425	Linker-PDZ	2VWR
MAGI1	Membrane associated guanylate kinase WW and PDZ containing protein 1, 4th PDZ domain	Q96QZ7	839-922	Linker-PDZ	2Q9V
MAGI1	Membrane associated guanylate kinase WW and PDZ containing protein 1, 6th PDZ domain containing C1190S mutant	Q96QZ7	1149-1233	Linker-PDZ	2R4H
MAGI1	Membrane associated guanylate kinase WW and PDZ containing protein 1, 3th PDZ domain continaing double mutant, C677S and C709S	Q96QZ7	640-721	Linker-PDZ	3BPU
MPDZ	Multiple PDZ domain protein, 1st PDZ domain	O75970	117-227	Linker-PDZ	2O2T
MPDZ	Multiple PDZ domain protein, 3rd PDZ domain	O75970	373-463	Linker-PDZ	2IWN
MPDZ	Multiple PDZ domain protein, 7th PDZ domain	O75970	1148-1243	Linker-PDZ	2FCF
MPDZ	Multiple PDZ domain protein, 12th PDZ domain	O75970	1858-1951	Linker-PDZ	2IWO
MPDZ	Multiple PDZ domain protein, 13th PDZ domain	O75970	1983-2070	Linker-PDZ	2FNE
MPDZ	Multiple PDZ domain protein, 10th PDZ domain	O75970	1625-1716	Linker-PDZ	2OPG
MPDZ	Multiple PDZ domain protein, 11th PDZ domain	O75970	1722-1806	Linker-PDZ	2QG1
NHERF1	Na(+)/H(+) exchange regulatory cofactor NHE-RF1, PDZ domain	O14745	150-235	Linker-PDZ	2OZF
NHERF2	Na(+)/H(+) exchange regulatory cofactor NHE-RF2, PDZ domain	Q15599	147-230	Linker-PDZ	2HE4
NHERF2	Na(+)/H(+) exchange regulatory cofactor NHE-RF2, PDZ domain	Q15599	9-91	Linker-PDZ	2OCS
NHERF4	Na(+)/H(+) exchange regulatory cofactor NHE-RF4, PDZ domain	Q86UT5	326-419	Linker-PDZ	2V90
PDLIM1	PDZ and LIM domain protein 1, PDZ domain	O00151	1-87	Linker-PDZ	2PKT
PDLIM2	PDZ and LIM domain protein 2, PDZ domain	Q96JY6	1-82	Linker-PDZ	2PA1
PDLIM4	PDZ and LIM domain protein 4, PDZ domain	P50479	1-87	Linker-PDZ	2V1W
PDLIM5	PDZ and LIM domain protein 5, PDZ domain	Q96HC4	1-85	Linker-PDZ	2UZC
PDLIM7	PDZ and LIM domain protein 7, PDZ domain	Q9NR12	1-84	Linker-PDZ	2Q3G
PDZK1	Na(+)/H(+) exchange regulatory cofactor NHE-RF3, PDZ domain	Q5T2W1	375-461	Linker-PDZ	2VSP
PICK1	RKCA-binding protein, PDZ domain	Q9NRD5	18-105	Linker-PDZ	2GZV
RHPN2	Rhophilin-2, PDZ domain	Q8IUC4	514-598	Linker-PDZ	2VSV
SCRIB	Protein scribble homolog, PDZ domain	Q14160	725-815	Linker-PDZ	2W4F
SNTB2	Beta-2-syntrophin, PDZ domain	Q13425	112-200	Linker-PDZ	2VRF
SYNJ2BP	Synaptojanin 2 binding protein, PDZ domain	P57105	5-101	Linker-PDZ	2JIK
TAMALIN	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, PDZ domain	Q7Z6J2	97-192	Linker-PDZ	2PNT
TAX1BP3	Tax1-binding protein 3, PDZ domain	O14907	11-124	Linker-PDZ	2VZ5
ACOT11	Acyl-coenzyme A thioesterase 11, START domain	Q8WXI4	339-543	Lipid signaling-Other	3FO5
ACOT12	Acyl-coenzyme A thioesterase	Q8WYK0	7-316	Lipid signaling-Other	3B7K
ACOT4	Peroxisomal succinyl-coenzyme A thioesterase	Q8N9L9	1-421	Lipid signaling-Other	3K2I
ACOT7	Cytosolic acyl coenzyme A thioester hydrolase	O00154	209-378	Lipid signaling-Other	2QQ2
bphA4	Biphenyl dioxygenase ferredoxin reductase subunit	E7FJB9	1-408	Lipid signaling-Other	2H4U
EPB41L3	Band 4.1-like protein 3, FERM domain	Q9Y2J2	108-390	Lipid signaling-Other	2HE7/3BIN
FABP1	Fatty acid-binding protein, liver	P07148	1-127	Lipid signaling-Other	2F73
STARD13	StAR-related lipid transfer protein 13, START domain	Q9Y3M8	903-1113	Lipid signaling-Other	2PSO
STARD5	StAR-related lipid transfer protein 5, START domain	QN9SY2	6-213	Lipid signaling-Other	2R55
LCN15	Lipocalin-15	Q6UWW0	19-177	Lipocalin	2XST
PMP2	Myelin P2 protein	P02689	3-132	Lipocalin	3NR3
CA13	Carbonic anhydrase 13	Q8N1Q1	1-261	Lyase-Carbonic-Anhydrase	3DA2
CA6	Carbonic anhydrase 6	P23280	20-290	Lyase-Carbonic-Anhydrase	3FE4
CA7	Carbonic anhydrase 7	P43166	5-262	Lyase-Carbonic-Anhydrase	3MDZ
CA8	Carbonic anhydrase-related protein	P35219	1-290	Lyase-Carbonic-Anhydrase	2W2J
HTD2	Hydroxyacyl-thioester dehydratase type 2, mitochondrial	P86397	23-168	Lyase-Other	3IR3
MLYCD	Malonyl-CoA decarboxylase	O95822	40-490	Lyase-Other	2YGW
MAGEA4	Melanoma antigen family A, 4	P43358	99-317	MAGE	2WA0
RAMP2	Receptor activity-modifying protein 2	O60895	48-139	Membrane-GPCR	2XVT
GHRHR	Growth hormone-releasing hormone receptor	Q02643	34-123	Membrane-GPCR-ECD	2XDG
VIPR2	Vasoactive intestinal polypeptide receptor 2, hormone receptor domain	P41587	26-118	Membrane-GPCR-ECD	2X57
ELAC1	Zinc phosphodiesterase ELAC protein 1	Q9H777	3-363	Metallo-Beta-Lactamase? Zinc phosphodiesterase	3ZWF
HSP90B1	Heat shock protein HSP 90-beta	P08238	284-543	Miscellaneous	3PRY
MMACHC	Cyanocobalamin reductase or alkylcobalamin dealkylase	Q9Y4U1	1-282	Miscellaneous	3SOM
TATDN1	Deoxyribonuclease TATDN1	Q6P1N9	5-295	Miscellaneous	2XIO
TATDN3	Putative deoxyribonuclease TATDN3	Q17R31	5-274	Miscellaneous	2Y1H
TP73	Tumor protein p73	O15350	112-311	Miscellaneous	2XWC
NUMBL	Numb-like protein	Q9Y6R0	60-204	Neuronal stem cell development	3F0W
TH	Tyrosine 3-monooxygenase	P07101	193-528	Neurotransmitter-Synthesis	2XSN
ADAT2	tRNA-specific adenosine deaminase 2	Q7Z6V5	20-185	Nucleotide metabolism-Deaminases	3DH1
GDAﾠﾠﾠ	Guanine deaminase	Q9Y2T3	1-454	Nucleotide metabolism-Deaminases	2UZ9
ITPKB	Inosine triphosphate pyrophosphatase	Q9BY32	1-194	Nucleotide metabolism-Nucleotide phosphatases	2CAR/2J4E
RRM1	Ribonucleoside-diphosphate reductase large subunit	P23921	75-742	Nucleotide metabolism-Nucleotide reductases	2WGH
RRM2	Ribonucleoside-diphosphate reductase subunit M2	P31350	60-389	Nucleotide metabolism-Nucleotide reductases	2UW2
RRM2B	Ribonucleoside-diphosphate reductase subunit M2 B	Q7LG56	17-322	Nucleotide metabolism-Nucleotide reductases	2VUX
NUDT1	Oxidized purine nucleoside triphosphate hydrolase	P36639	1-156	Nucleotide metabolism-NUDIX	3Q93
NUDT10	Diphosphoinositol polyphosphate phosphohydrolase 3-alpha	Q8NFP7	17-144	Nucleotide metabolism-NUDIX	3MCF
NUDT14	Uridine diphosphate glucose pyrophosphatase	O95848	28-222	Nucleotide metabolism-NUDIX	3Q91
NUDT16	U8 snoRNA-decapping enzyme	Q96DE0	1-195	Nucleotide metabolism-NUDIX	3COU/’2XSQ
NUDT16L1	Protein syndesmos	Q9BRJ7	6-211	Nucleotide metabolism-NUDIX	3KVH
NUDT18	8-oxo-dGDP phosphatase NUDT18	Q6ZVK8	26-179	Nucleotide metabolism-NUDIX	3GG6
NUDT21	Cleavage and polyadenylation specificity factor subunit 5	O43809	19-227	Nucleotide metabolism-NUDIX	2CL3
NUDT21	Cleavage and polyadenylation specificity factor subunit 5	O43809	20-227	Nucleotide metabolism-NUDIX	2J8Q
NUDT6	Nucleoside diphosphate-linked moiety X motif 6	P53370	141-316	Nucleotide metabolism-NUDIX	3FXT
ADSLﾠﾠﾠ	Adenylosuccinate lyase	P30566	1-481	Nucleotide metabolism-Others	2J91/2VD6
ADSS2	Adenylosuccinate synthetase isozyme 2	P30520	21-456	Nucleotide metabolism-Others	2V40
CTPS1	CTP synthase 1, synthase domain	P17812	1-273	Nucleotide metabolism-Others	2C5M/2VO1
CTPS2	CTP synthase 2, glutaminase domain	Q9NRF8	292-562	Nucleotide metabolism-Others	2V4U/2VKT
CTPS2	CTP synthase 2, synthase domain	Q9NRF8	1-275	Nucleotide metabolism-Others	3IHL
DCTDﾠﾠﾠ	Deoxycytidylate deaminase	P32321	4-174	Nucleotide metabolism-Others	2W4L
GART	Trifunctional purine biosynthetic protein adenosine-3	P22102	1-430	Nucleotide metabolism-Others	2QK4
GART	Trifunctional purine biosynthetic protein adenosine-3	P22102	467-794	Nucleotide metabolism-Others	2V9Y
GMPS	GMP synthetase [glutamine hydrolyzing], glutaminase domain	P49915	11-219	Nucleotide metabolism-Others	2VPI
GMPS	GMP synthetase [glutamine hydrolyzing]	P49915	20-693	Nucleotide metabolism-Others	2VXO
PRPSAP1ﾠﾠﾠ	Phosphoribosyl pyrophosphate synthase-associated protein 1	Q14558	1-351	Nucleotide metabolism-Others	2C4K
PRPSAP2	Phosphoribosyl pyrophosphate synthase-associated protein 2	O60256	12-369	Nucleotide metabolism-Others	2JI4
PRTFDC1	Phosphoribosyltransferase domain-containing protein 1	Q9NRG1	1-225	Nucleotide metabolism-Others	2JBH
UCK1	Uridine-cytidine kinase 1	Q9HA47	21-243	Nucleotide metabolism-Others	2JEO/2UVQ
UMPS	Uridine 5′-monophosphate synthase	P11172	224-479	Nucleotide metabolism-Others	2JGY/2V30
UMPS	Uridine 5′-monophosphate synthase	P11172	7-203	Nucleotide metabolism-Others	2WNS
UPP2	Uridine phosphorylase 2	O95045	23-317	Nucleotide metabolism-Others	2XRF
CCNT2	Cyclin-T2	O60583	7-263	Other-Cyclin	2IVX
ACBD4	Acyl-CoA-binding domain-containing protein 4	Q8NC06	7-110	Other-NonDR	2WH5
ACBD5	Acyl-CoA-binding domain-containing protein 5	Q5T8D3	41-136	Other-NonDR	3FLV
ACBD7	Acyl-CoA-binding domain-containing protein 7	Q8N6N7	1-88	Other-NonDR	3EPY
CRYBA4	Beta-crystallin A4	P53673	8-196	Other-NonDR	3LWK
CRYBB3	Beta-crystallin B3	P26998	21-199	Other-NonDR	3QK3
FDX1	Adrenodoxin, mitochondrial	P10109	61-184	Other-NonDR	3P1M
GMFG	Glia maturation factor gamma	O60234	7-140	Other-NonDR	3L50
LHPP	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase	Q9H008	1-270	Other-NonDR	2X4D
MMAA	Methylmalonic aciduria type A protein, mitocondrial	Q8IVH4	70-418	Other-NonDR	2WWW
TTC5	Tetratricopeptide repeat protein 5	Q8N0Z6	261-424	Other-Signal	2XVS
TWF2	Twinfilin-2	Q6IBS0	6-137	Other-Signal	2VAC
TWF2	Twinfilin-2	Q6IBS0	179-313	Other-Signal	2W0I
YWHAB	14-3-3 protein beta/alpha	P31946	1-240	Other-Signal	2BQ0
YWHAE	14-3-3 protein epsilon	P62258	1-233	Other-Signal	2BR9
YWHAG	14-3-3 protein gamma	P61981	2-247	Other-Signal	2B05
YWHAH	14-3-3 protein eta	Q04917	1-246	Other-Signal	2C74
YWHAQ	14-3-3 protein theta	P27348	1-234	Other-Signal	2BTP
ASPH	Aspartyl/asparaginyl beta-hydroxylase	Q12797	562-758	Oxidoreductase-2OG	3RCQ
BBOX1	Gamma-butyrobetaine dioxygenase	O75936	1-387	Oxidoreductase-2OG	3MS5
JMJD6	Bifunctional arginine demethylase and lysyl-hydroxylase	Q6NYC1	2-335	Oxidoreductase-2OG	3K2O
KDM4A	Lysine-specific demethylase 4A	O75164	1-359	Oxidoreductase-2OG	2OQ7
KDM4C	Lysine-specific demethylase 4C	Q9H3R0	875-995	Oxidoreductase-2OG	2XDP
KDM4E	Lysine-specific demethylase 4E	B2RXH2	1-336	Oxidoreductase-2OG	2W2I
KDM5C	Lysine-specific demethylase 5C	P41229	73-188	Oxidoreductase-2OG	2JRZ
KDM6B	Lysine-specific demethylase 6B	O15054	1176-1505	Oxidoreductase-2OG	2XXZ
PHF8	Histone lysine demethylase PHF8	Q9UPP1	115-483	Oxidoreductase-2OG	2WWU
PHYHD1	hytanoyl-CoA dioxygenase domain-containing protein 1	Q5SRE7	1-291	Oxidoreductase-2OG	2OPW
ACAD11	Acyl-CoA dehydrogenase family member 11	Q709F0	353-780	Oxidoreductase-Acyl-CoA	2WBI
ACADS	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	P16219	30-412	Oxidoreductase-Acyl-CoA	2VIG
ACADSB	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	P45954	52-432	Oxidoreductase-Acyl-CoA	2JIF
ACADVL	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	P49748	69-655	Oxidoreductase-Acyl-CoA	2UXW
AKR1C4	Aldo-keto reductase family 1 member C4	P17516	1-323	Oxidoreductase-AKR	2FVL
AKR7A2	Aflatoxin B1 aldehyde reductase member 2	O43488	1-359	Oxidoreductase-AKR	2BP1
AKR7A3	Aflatoxin B1 aldehyde reductase member 3	O95154	6-331	Oxidoreductase-AKR	2CLP
ALDH18A1	Delta-1-pyrroline-5-carboxylate synthase	P54886	362-795	Oxidoreductase-ALDH	2H5G
ALDH7A1	Alpha-aminoadipic semialdehyde dehydrogenase	P49419	29-527	Oxidoreductase-ALDH	2J6L
GPX1	Glutathione peroxidase 1	P07203	14-198	Oxidoreductase-GPX	2F8A
GPX2	Glutathione peroxidase 2	P18283	4-188	Oxidoreductase-GPX	2HE3
GPX3	Glutathione peroxidase 3	P22352	25-223	Oxidoreductase-GPX	2R37
GPX4	Glutathione peroxidase 4	P36969	36-197	Oxidoreductase-GPX	2GS3
GPX5	Epididymal secretory glutathione peroxidase	O75715	28-220	Oxidoreductase-GPX	2I3Y
GPX7	Glutathione peroxidase 7	Q96SL4	20-177	Oxidoreductase-GPX	2P31
GPX8	Probable glutathione peroxidase 8	Q8TED1	44-209	Oxidoreductase-GPX	3CYN
ADH4	All-trans-retinol dehydrogenase [NAD(+)] ADH4	P08319	1-380	Oxidoreductase-MDR	3COS
FASN	Fatty acid synthase	P49327	422-831	Oxidoreductase-MDR	2JFK
MECR	Enoyl-[acyl-carrier-protein] reductase, mitochondrial	Q9BV79	40-373	Oxidoreductase-MDR	1ZSY
PTGR1	Prostaglandin reductase 1	Q14914	4-329	Oxidoreductase-MDR	1ZSV
PTGR2	Prostaglandin reductase 2	Q8N8N7	1-350	Oxidoreductase-MDR	2VNA
PTGR3	Prostaglandin reductase 3	Q8N4Q0	33-371	Oxidoreductase-MDR	2C0C
PTGR3	Prostaglandin reductase 3	Q8N4Q0	31-370	Oxidoreductase-MDR	2WEK
RTN4IP1	Reticulon-4-interacting protein 1, mitochondrial	Q8WWV3	45-396	Oxidoreductase-MDR	2VN8
TP53I3	Quinone oxidoreductase PIG3	Q53FA7	1-332	Oxidoreductase-MDR	2J8Z
BLVRA	Biliverdin reductase A	P53004	7-296	Oxidoreductase-Other	2H63
CRYL1	Lambda-crystallin homolog	Q9Y2S2	6-316	Oxidoreductase-Other	3F3S
CTBP2	C-terminal binding protein 2	P56545	31-364	Oxidoreductase-Other	2OME
GAPDHS	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific	O14556	69-407	Oxidoreductase-Other	3H9E
GLOD5	Glyoxalase domain-containing protein 5	A6NK44	34-157	Oxidoreductase-Other	3ZW5
GLRX2	Glutaredoxin-2, mitochondrial	Q9NS18	41-164	Oxidoreductase-Other	2HT9
GLRX2	Glutaredoxin-2, mitochondrial	Q9NS18	56-164	Oxidoreductase-Other	2FLS
GLRX3	Glutaredoxin-3	O76003	1-134	Oxidoreductase-Other	2WZ9
GLRX3	Glutaredoxin-3	O76003	232-334	Oxidoreductase-Other	2YAN
GLYR1	Cytokine-like nuclear factor N-PAC	Q49A26	261-553	Oxidoreductase-Other	2UYY
GMPR	GMP reducatse 1	P36959	1-345	Oxidoreductase-Other	2BLE
GPD1L	Glycerol-3-phosphate dehydrogenase 1-like protein	Q8N335	1-349	Oxidoreductase-Other	2PLA
HAO1	2-Hydroxyacid oxidase 1	Q9UJM8	1-370	Oxidoreductase-Other	2NZL
HIBADH	3-Hydroxyisobutyrate dehydrogenase, mitochondrial	P31937	41-335	Oxidoreductase-Other	2GF2
HPD	4-hydroxyphenylpyruvate dioxygenase	P32754	8-393	Oxidoreductase-Other	3ISQ
MCEE	Methylmalonyl CoA epimerase	Q96PE7	45-176	Oxidoreductase-Other	3RMU
MDH2	Malate dehydrogenase 2, NAD (mitochondrial)	P40926	19-338	Oxidoreductase-Other	2DFD
ME1	NADP-dependent malic enzyme	P48163	13-564	Oxidoreductase-Other	2AW5
MSRB1	Methionine-R-sulfoxide reductase B1	Q9NZV6	10-112	Oxidoreductase-Other	3MAO
PGD	6-phosphogluconate dehydrogenase, decarboxylating	P52209	1-483	Oxidoreductase-Other	2JKV
PHGDH	D-3-phosphoglycerate dehydrogenase	O43175	4-314	Oxidoreductase-Other	2G76
PRDX4	Peroxiredoxin 4	Q13162	84-271	Oxidoreductase-Other	2PN8
PYCR1	Pyrroline-5-carboxylate reductase 1, mitochondrial	P32322	1-300	Oxidoreductase-Other	2IZZ
TXNRD1	Thioredoxin reductase 1, cytoplasmic	Q16881	150-649	Oxidoreductase-Other	2CFY
TXNRD3	Thioredoxin reductase 3	Q86VQ6	51-156	Oxidoreductase-Other	3H8Q
UGDH	UDP-glucose 6-dehydrogenase	O60701	1-466	Oxidoreductase-Other	2Q3E
BDH2	Dehydrogenase/reductase SDR family member 6	Q9BUT1	1-245	Oxidoreductase-SDR	2AG5
CBR3	Carbonyl reductase [NADPH] 3	O75828	6-277	Oxidoreductase-SDR	2HRB
DHRS1	Dehydrogenase/reductase SDR family member 1	Q96LJ7	3-262	Oxidoreductase-SDR	2QQ5
DHRS11	Dehydrogenase/reductase SDR family member 11	Q6UWP2	1-256	Oxidoreductase-SDR	1XG5
DHRS4	Dehydrogenase/reductase SDR family member 4	Q9BTZ2	19-278	Oxidoreductase-SDR	3O4R
GMDS	GDP-mannose 4,6-dehydratase	O60547	23-372	Oxidoreductase-SDR	1T2A
HPGD	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	P15428	3-256	Oxidoreductase-SDR	2GDZ
HSD11B1	11-Beta-hydroxysteroid dehydrogenase 1	P28845	20-284	Oxidoreductase-SDR	2BEL
HSD17B10	3-hydroxyacyl-CoA dehydrogenase type-2	Q99714	1-261	Oxidoreductase-SDR	2O23
HSD17B11	Estradiol 17-beta-dehydrogenase 11	Q8NBQ5	15-275	Oxidoreductase-SDR	1YB1
HSD17B14	17-Beta-hydroxysteroid dehydrogenase 14	Q9BPX1	1-270	Oxidoreductase-SDR	1YDE
HSD17B4	Peroxisomal multifunctional enzyme type 2	P51659	1-304	Oxidoreductase-SDR	1ZBQ
HSD17B8	(3R)-3-hydroxyacyl-CoA dehydrogenase	Q92506	6-261	Oxidoreductase-SDR	2PD6
MAT2B	MAT2B: methionine adenosyltransferase II, beta [RefSeq, isoform 2] (aka TGR, MAT-II, MGC12237, MATIIbeta, Nbla02999)	Q9NZL9	28-334	Oxidoreductase-SDR	2YDX
NMRAL1	NmrA-like family domain containing protein 1	Q9HBL8	1-298	Oxidoreductase-SDR	2WMD
PECR	Peroxisomal trans-2-enoyl-CoA reductase	Q9BY49	1-303	Oxidoreductase-SDR	1YXM
SPR	Sepiapterin reductase	P35270	5-261	Oxidoreductase-SDR	1Z6Z
UXS1	UDP-glucuronic acid decarboxylase 1	Q8NBZ7	85-402	Oxidoreductase-SDR	2B69
PARP10	Protein mono-ADP-ribosyltransferase PARP10	Q53GL7	809-1017	PARP	3HKV
PARP12	Protein mono-ADP-ribosyltransferase PARP12	Q9H0J9	489-684	PARP	2PQF
PARP14	Protein mono-ADP-ribosyltransferase PARP14	Q460N5	1611-1801	PARP	3GOY
PARP15	Protein mono-ADP-ribosyltransferase PARP15	Q460N3	459-656	PARP	3BLJ/3GEY
PARP2	Poly [ADP-ribose] polymerase 2	Q9UGN5	235-579	PARP	3KCZ/3KJD
PARP3	Protein mono-ADP-ribosyltransferase PARP3	Q9Y6F1	178-532	PARP	2PA9/3C49/3C4H/3CE0/3FHB
TNKS1	Poly [ADP-ribose] polymerase tankyrase-1	O95271	1091-1325	PARP	2RF5
TNKS2	Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	946-1162	PARP	3KR7/3P0Q/3P0P/3KR8/3MHJ/3P0N
TNKS2	Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	955-1162	PARP	3MHK
ZC3HAV1	Zinc finger CCCH-type antiviral protein 1	Q7Z2W4	724-896	PARP	2X5Y
PARP14	Protein mono-ADP-ribosyltransferase	Q460N5	999-1196	PARP domain	3Q71
PARP14	Protein mono-ADP-ribosyltransferase	Q460N5	789-979	PARP domain	3Q6Z
pcp	Pyrrolidone-carboxylate peptidase	Q5HCK7	1-212	Pathogen	3G1U
Processed	CTP synthase	Q4GZ95	319-589	Pathogen	2W7T
TRYB2	Adenosylhomocysteinase	Q383X0	4-437	Pathogen	3H9U
ANLN	Anillin	Q9NQW6	980-1113	PH-Domain	2Y7B
CDC25C	M-phase inducer phosphatase 3	P30307	270-462	Phosphatase-Dual-Spec	3OP3
DUSP13	Dual specificity protein phosphatase 13B	Q9UII6	1-198	Phosphatase-Dual-Spec	2PQ5
DUSP16	Dual specificity protein phosphatase 16	Q9BY84	5-150	Phosphatase-Dual-Spec	2VSW
PGAM5	Serine/threonine-protein phosphatase, mitochondrial	Q96HS1	90-289	Phosphatase-Dual-Spec	3MXO
RNGTT	mRNA-capping enzyme	O60942	1-219	Phosphatase-Other	2C46
PTPRB	Receptor-type tyrosine-protein phosphatase beta	P23467	1686-1971	Phosphatase-Tyr-Receptor	2AHS
PTPRE	Receptor-type tyrosine-protein phosphatase epsilon	P23469	107-697)	Phosphatase-Tyr-Receptor	2JJD
PTPRG	Receptor-type tyrosine-protein phosphatase epsilon	P23470	827-1445	Phosphatase-Tyr-Receptor	2NLK
PTPRJ	Receptor-type tyrosine-protein phosphatase eta	Q12913	1019-1311	Phosphatase-Tyr-Receptor	2H4V
PTPRJ	Receptor-type tyrosine-protein phosphatase eta	Q12913	1016-1311	Phosphatase-Tyr-Receptor	2CFV
PTPRK	Receptor-type tyrosine-protein phosphatase eta	Q15262	865-1154	Phosphatase-Tyr-Receptor	2NZ6
PTPRK	Receptor-type tyrosine-protein phosphatase kappa	Q15262	853-1154	Phosphatase-Tyr-Receptor	2C7S
PTPRN2	Receptor-type tyrosine-protein phosphatase N2	Q92932	715-1010	Phosphatase-Tyr-Receptor	2QEP
PTPRO	Receptor-type tyrosine-protein phosphatase O	Q16827	916-1208	Phosphatase-Tyr-Receptor	2GJT
PTPRR	Receptor-type tyrosine-protein phosphatase R	Q15256	375-655	Phosphatase-Tyr-Receptor	2A8B
PTPRT	Receptor-type tyrosine-protein phosphatase T	O14522	868-1151	Phosphatase-Tyr-Receptor	2OOQ
PTPN11	Tyrosine-protein phosphatase, non-receptor type 11	Q06124	237-529	Phosphatase-Tyr-Soluble	3B7O
PTPN14	Tyrosine-protein phosphatase non-receptortype 14	Q15678	886-1187	Phosphatase-Tyr-Soluble	2BZL
PTPN18	Tyrosine-protein phosphatase non-receptor type 18	Q99952	6-299	Phosphatase-Tyr-Soluble	2OC3
PTPN22	Tyrosine-protein phosphatase non-receptor type 22	Q9Y2R2	1-302	Phosphatase-Tyr-Soluble	2P6X
PTPN3	Tyrosine-protein phosphatase non-receptor type 3	P26045	628-913	Phosphatase-Tyr-Soluble	2B49
PTPN4	Tyrosine-protein phosphatase non-receptor type 4	P29074	611-926	Phosphatase-Tyr-Soluble	2I75
PTPN4	Tyrosine-protein phosphatase non-receptor type 4, PDZ domain	P29074	513-610	Phosphatase-Tyr-Soluble	2VPH
PTPN5	Tyrosine-protein phosphatase non-receptor type 5	P54829	277-563	Phosphatase-Tyr-Soluble	2CJZ
PTPN5	Tyrosine-protein phosphatase non-receptor type 5	P54829	282-563	Phosphatase-Tyr-Soluble	2BV5
PTPN7	Tyrosine-protein phosphatase non-receptor type 7	P35236	65-358	Phosphatase-Tyr-Soluble	2A3K
PTPN9	Tyrosine-protein phosphatase non-receptor type 9	P43378	277-582	Phosphatase-Tyr-Soluble	2PA5
MTMR6	Myotubularin-related protein 6	Q9Y217	1-505	Phosphatases
NANP	N-acylneuraminate-9-phosphatase	Q8TBE9	1-248	Phosphatases	2W4M
MTMR6	Myotubularin-related protein 6	Q9Y217	1-507	Phosphatases – Other	2YF0
PHPT1	14 kDa phosphohistidine phosphatase	Q9NRX4	5-125	Phosphatases – Other	2HW4
PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	Q13362	11-380	Phosphatases – Other	2JAK
PTPA	Serine/threonine-protein phosphatase 2A activator	Q15257	22-358	Phosphatases – Other	2G62
THTPA	Thiamine-triphosphatase	Q9BU02	1-215	Phosphatases – Other	3BHD
NISCH	Nischarin, PX-domain	Q9Y2I1	18-124	Phosphoinositide dependent signaling – Lipid binding domains	3P0C
SNX7	Sorting nexin-7, Pxdomain	Q9UNH6	25-154	Phosphoinositide dependent signaling – Lipid binding domains	3IQ2
TULP1	Tubby-related protein 1, Tub family domain	O00294	290-542	Phosphoinositide dependent signaling – Lipid binding domains	2FIM/3C5N
NUDT3	Diphosphoinositol polyphosphate phosphohydrolase 1	O95989	1-172	Phosphoinositide dependent signaling – Lipid phosphatases	2FVV/2Q9P
MIOX	Inositol oxygenase	Q9UGB7	38-285	Phosphoinositide dependent signaling – Others	2IBN
SNX17	Sorting nexin-17, PX domain	Q15036	1-108	Phosphoinositide dependent signaling – Others	3FOG
IMPA2	Inositol monophosphatase 2	O14732	16-288	Phosphoinositide dependent signaling – PIP-Phosphatases	2FVZ
INPP5B	Type II inositol 1,4,5-trisphosphate 5-phosphatase	P32019	339-643	Phosphoinositide dependent signaling – PIP-Phosphatases	3MTC
INPP5B	Type II inositol 1,4,5-trisphosphate 5-phosphatase	P32019	341-646	Phosphoinositide dependent signaling – PIP-Phosphatases	3N9V
INPP5E	Phosphatidylinositol polyphosphate 5-phosphatase type IV	Q9NRR6	275-623	Phosphoinositide dependent signaling – PIP-Phosphatases	2XSW
INPPL1	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	O15357	419-732	Phosphoinositide dependent signaling – PIP-Phosphatases	3NR8
DNPEP	Aspartyl aminopeptidase	Q9ULA0	1-478	Protease-Other	3L6S (4DYO)
G3BP1	Ras GTPase-activating protein-binding protein 1, NTF2 domain	Q13283	1-139	Receptor Signaling Domains	3Q90
SKIL	Ski-like protein	P12757	137-238	Receptor Signaling Domains	3EQ5
TLR10	Toll-like receptor 10, TIR domain	Q9BXR5	622-776	Receptor Signaling Domains	2J67
NUDT21	Cleavage and polyadenylation specificity factor subunit 5	O43809	21-227	RNA processing	3N9U
LASP1	LIM and SH3 domain protein 1, SH3 domain	Q14847	202-261	SH3 domain	3I35
SOCS6	Suppressor of cytokine signaling 6, SH2 domain	O14544	361-499	SOCS-box-containing	2VIF
SPSB1	SPRY domain-containing SOCS box protein 1	Q96BD6	24-233	SOCS-box-containing	2JK9
SPSB2	SPRY domain-containing SOCS box protein 2	Q99619	26-219	SOCS-box-containing	3EMW
SPSB4	SPRY domain-containing SOCS box protein 4	Q96A44	28-233	SOCS-box-containing	2V24
AMPH	Amphiphysin	P49418	34-236	To be assigned	3SOG
ENO3	Beta-enolase	P13929	1-434	To be assigned	2XSX
GYG1	Glycogenin 1	P46976	1-262	To be assigned	3Q4S
HBP1	HMG-box transcription factor 1	O60381	206-342	To be assigned	3QVE
MACROH2A2	Core histone macro-H2A.2	Q9P0M6	177-369	To be assigned	2XD7
EBF1	Transcription factor COE1, DNA binding domain	Q9UH73	10-250	Transcription-Factor	3LYR
EBF1	Transcription factor COE1, IPT/TIG domain	Q9UH73	258-351	Transcription-Factor	3MQI
EBF3	Transcription factor COE3, IPT/TIG domain	Q9H4W6	261-395	Transcription-Factor	3MUJ
EBF3	Transcription factor COE3, IPT/TIG domain, helix-loop-helix domain	Q9H4W6	261-415	Transcription-Factor	3N50
ACAA1	3-ketoacyl-CoA thiolase, peroxisomal	P09110	30-424	Transferase	2IIK
FDPS	Farnesyl pyrophosphate synthase	P14324	67-419	Transferase	2QIS
GGPS1	Geranylgeranyl pyrophosphate synthase	O95749	1-300	Transferase	2Q80
GOT1	Aspartate aminotransferase 1, cytoplasmic	P17174	14-412	Transferase	3II0
HMGCS1	Hydroxymethylglutaryl-CoA synthase, cytoplasmic	Q01581	16-470	Transferase	2P8U
HMGCS2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)			Transferase	2V4W
MAT1A	Methionine adenosyltransferase I, alpha	Q00266	16-395	Transferase	2OBV
MAT2A	Methionine adenosyltransferase II, alpha	P31153	1-395	Transferase	2P02
MCAT	Malonyl-CoA:acyl carrier protein transacylase (malonyltransferase) [isoform 1]	Q8IVS2	60-375	Transferase	2C2N
OXCT1	3-oxoacid CoA transferase	P55809	40-520	Transferase	3DLX
OXSM	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial	Q9NWU1	39-459	Transferase	2C9H
TKT	Transketolase	P29401	10-620	Transferase	3OOY
TGM1	Protein-glutamine gamma-glutamyltransferase K, Ig domain	P22735	693-787	Transglutaminase	2XZZ
ARNT	Aryl hydrocarbon receptor nuclear translocator	P27540	356-470	Various other targets
BAK1	Bcl-2 homologous antagonist/killer, mitochondrial apoptosis regulator	Q16611	21-190	Various other targets	2JCN
BCL2A1	Bcl-2-related protein A1	Q16548	1-149	Various other targets	2VM6
EPAS1	Endothelial PAS domain-containing protein 1	Q99814	239-350	Various other targets
GLS	Glutaminase kidney isoform, mitochondrial	O94925	221-533	Various other targets	3CZD
NT5C2	Cytosolic purine 5′-nucleotidase	P49902	1-536	Various other targets	2J2C/2JC9/2JCM
NT5C3	Cytosolic 5′-nucleotidase 3A	Q9H0P0	64-336	Various other targets	2CN1/2JGA/2VKQ
NUDT	Oxidized purine nucleoside triphosphate hydrolase	P36639	42-197	Various other targets
SYN3	Synapsin 3	O14994	76-417	Vesicle-Transport	2P0A
ZFYVE16	Zinc finger FYVE domain-containing protein 16, FYVE zinc finger domain	Q7Z3T8	733-820	zinc finger domain	3T7L
PKM2	Pyruvate kinase isozymes	P14618	3-530

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