FastLane™ Structure Libraries

X-ray crystallography services at SARomics Biostructures are run at our cutting-edge, high-throughput pipeline anchored by our FastLane™ Premium and FastLane™ Standard libraries.

X-ray crystallography services - FastLane premium library

FastLane™ Premium Structures

Library of verified drug targets that have already been expressed, purified, and crystallized at the company (off-the-shelf structures). Purified proteins are available for the immediate start of a project.

X-ray crystallography services - FastLane standard library

FastLane™ standard

Library of verified drug targets for which expression plasmids and protocols for expression, purification, and crystallization are available at the company.

FastLane™ Structures Libraries of Proteins and constructs

Our FastLane™ Premium and FastLane™ Standard libraries boast 500+ verified drug targets ready to be directly crystallized with your chosen ligand (FastLane™ Premium) or expressed, purified, and crystallized according to verified protocols (FastLane™ Standard) within a few weeks.

Please find below the details of our FastLane™ Premium and FastLane™ Standard libraries of off-the-shelf drug-target proteins. To explore the experimental details of our X-ray crystallography technology platform, please visit our methods and technologies knowledge center.

the FastLane™ Premium Library

The FastLane™ Premium library currently contains drug-target proteins ready for co-crystallization with ligands. The library includes an extensive collection of kinases, phosphatases, proteases, epigenetic factors, and other drug targets. Using our high-throughput X-ray crystallography services pipeline, the turnaround time for structure determination for these proteins is between 2 to 8 weeks (depending on the protein).

GeneProtein
BTKTyrosine-protein kinase BTK
CDK2Cyclin-dependent kinase 2
CDK5Cyclin-dependent-like kinase 5
CDK7Cyclin-dependent-like kinase 7
CK2Casein kinase II subunit alpha
CLK3Dual specificity protein kinase CLK3
DAPK3Death-associated protein kinase 3
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A
EPHA7Ephrin type-A receptor 7
FGFR1Fibroblast growth factor receptor 1
FRKNon-receptor tyrosine-protein kinase
ITKTyrosine-protein kinase ITK/TSK
KITTyrosine-protein kinase, Mast/stem cell growth factor receptor Kit
LATS2Serine/threonine-protein kinase LATS2
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4
GeneProtein
NDR2Serine/threonine-protein kinase 38-like
PFKFB36-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
RSK1RPS6KA1 Ribosomal protein S6 kinase alpha-1
RSK2Ribosomal protein S6 kinase
SRPK1SRSF protein kinase 1
STK10LOK or Serine/threonine-protein kinase 10
STK17ADRAK1 or Serine/threonine-protein kinase 17A
STK17BDRAK2 or Serine/threonine-protein kinase 17B
TYK2Non-receptor tyrosine-protein kinase TYK2
Vps34PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3
VRK1Serine/threonine-protein kinase VRK1
VRK2Serine/threonine-protein kinase VRK2

GeneProtein
ATAD2AATPase family AAA domain-containing protein 2
ATAD2BATPase family AAA domain-containing protein 2B
JMJD2CKDM4C Lysine-specific demethylase 4C
SMARCA2BProbable global transcription activator SNF2L2
  

GeneProtein
CathepsinCCPPI, Dipeptidyl peptidase 1
DPP4Dipeptidyl peptidase 4
ThrombinF2, Human alpha thrombin
PTPN1PTP1B, Tyrosine-protein phosphatase non-receptor type 1
SHP2PTPN11, Tyrosine-protein phosphatase non-receptor type 11
USP21UBP21, Ubiquitin carboxyl-terminal hydrolase 21
USP7UBP7, Ubiquitin carboxyl-terminal hydrolase 7
USP8UBP8, Ubiquitin carboxyl-terminal hydrolase 8

GeneProtein
ALBHuman albumin, HSA
BCAT2Branched-chain-amino-acid aminotransferase, mitochondrial
BCL2A1BFL1, Bcl-2-related protein A1
BSSLBile salt-activated lipase
CD11bHuman Integrin alpha M
CD28T-cell-specific surface glycoprotein CD28
CD47Leukocyte surface antigen CD47
CD137TNFRSF9, Tumor necrosis factor receptor superfamily member 9
CGASCyclic GMP-AMP synthase
DHODHDihydroorotate dehydrogenase
EIF4EEukaryotic translation initiation factor 4E
Gal-1LGALS1, recombinant Galectin-1
Gal-3CLGALS3, recombinant Galectin-3 C-terminal carbohydrate binding domain
Gal-8NLGALS8, recombinant Galectin 8 N-terminal carbohydrate binding domain
Gal-9NLGALS9, recombinant Galectin 9, N-terminal carbohydrate binding domain
Gal-9CLGALS9, recombinant Galectin 9 C-terminal carbohydrate binding domain
GARTTrifunctional purine biosynthetic protein adenosine-3 (a.a. 808-1010)
GMPR2GMP reductase 2
HER2Receptor protein-tyrosine kinase extracellular domain
HSP90Heat shock protein HSP 90-alpha
GeneProtein
IL-4Recombinant Interleukin-4
IL-13Recombinant Interleukin-13
IL-17ARecombinant Interleukin-17A
IL-23IL-23A, Interleukin-23, subunits alpha and beta
K-Ras-cys mutRecombinant GTPase K-Ras
K-RasG12CRecombinant GTPase K-Ras G12C
K-RasG12DRecombinant GTPase K-Ras G12D
K-RasG12VRecombinant GTPase K-Ras G12C
LDHALDHA, L-lactate dehydrogenase A chain (rabbit)
NRP1Neuropilin-1
PD-1PDCD1, Programmed cell death 1
PD-L1PDL1, Programmed cell death 1 ligand 1
PDE4DcAMP-specific 3′,5′-cyclic phosphodiesterase 4D
PPARgammaPeroxisome proliferator-activated receptor gamma
PSD95DLG4, Disks large homolog 4
RORgammaNuclear receptor ROR-gamma
S100A12Protein S100-A12
S100A4Mts1 or Protein S100-A4
S100A9MRP14, Protein S100-A9
TNF-alphaTumor necrosis factor
TL1ATumor necrosis factor ligand superfamily member 15
TUBA1ATubulin alpha-1A (pig)
UbiquitinUbiquitin-60S ribosomal protein L40

GeneProtein
blaCBeta-lactamase (M. tuberculosis)
gyrBDNA gyrase subunit B (S. aureus)
SnfLeuT, Na(+):neurotransmitter symporter, Snf family (Aquifex aeolicus VF5)
SARS CoV-2 RBDSpike glycoprotein receptor-binding domain (SARS-CoV-2)
SARS CoV-2 RBD betaSpike glycoprotein receptor-binding domain, B.1.351 variant (SARS-CoV-2)
contact SARomics Biostructures to discuss your structural biology project

SARomics Biostructure’s X-ray crystallography services are leveraged by our location close to the MAX IV Laboratory in Lund, one of the most advanced synchrotron radiation facilities in the world.

the FastLane™ Standard Library

The FastLane™ Standard library currently contains around 500 constructs of drug target proteins ready for expression, purification, crystallization, and X-ray crystallographic structure determination according to verified protocols. The library includes a large number of protein kinases, phosphatases, epigenetic factors, and many other drug targets. Using our high-throughput protein X-ray crystallography pipeline, the turnaround time for structure determination for these proteins is between 6 to 12 weeks (depending on the protein).

How to search the table
The table can be serched by individual protein name or a whole protein family. For example, entering “kinase” in the search field will return a list of all kinases in the library. The protein families with largest number of entries in the library may be found using the search terms amino acid metabolic enzyme, phosphatase, bromodomain, epigenetic targets, oxidoreductase, ATPase, GTPase, nucleotide metabolism, BTB-Kelch, transferase, G-protein regulator, lipid signalling, PDZ domain, phosphoinositide dependent signalling, transferase and hydrolase.

GeneProtein nameUniProt IDSequence rangeProtein familyPDB ID
AHCYL1S-adenosylhomocysteine hydrolase-like protein 1O4386589-530amino acid metabolic enzymes3MTG
AHCYL2Adenosylhomocysteinase 3, NAD binding domainQ96HN2175-607amino acid metabolic enzymes3GVP
ASS1Argininosuccinate synthaseP009661-412amino acid metabolic enzymes2NZ2
CSADCysteine sulfinic acid decarboxylaseQ9Y6001-493amino acid metabolic enzymes2JIS
CTHCystathionine gamma-lyaseP329291-402amino acid metabolic enzymes2NMP/3COG
GLULGlutamine synthetase P151045-365amino acid metabolic enzymes2OJW
GPT2Alanine aminotransferase 2Q8TD3049-523amino acid metabolic enzymes3IHJ
MPST3-mercaptopyruvate sulfurtransferase P2532511-289amino acid metabolic enzymes3OLH
PCYT2Ethanolamine-phosphate cytidylyltransferase Q9944718-356amino acid metabolic enzymes3ELB
PSAT1Phosphoserine aminotransferaseQ9Y61717-370amino acid metabolic enzymes
SCLYSelenocysteine lyase Q96I158-445amino acid metabolic enzymes2HDY/3GZC/3GZD
TATTyrosine aminotransferase P1773541-444amino acid metabolic enzymes3DYD
GFPT1Glutamine–fructose-6-phosphate aminotransferase [isomerizing] 1, isomerase domain Q06210332-649Aminotransferas2V4M
BIRC3Baculoviral IAP repeat-containing protein 3, BIR domain Q13489242-337Apoptosis-Inflammation Domains2UVL
NAIPBaculoviral IAP repeat-containing protein 1, BIR2 domainQ13075139-244Apoptosis-Inflammation Domains2VM5
ALOX12 Polyunsaturated fatty acid lipoxygenaseP18054172-663Arachidonic acid metabolism3D3L
PTGDSProstaglandin-H2 D-isomeraseP4122223-190Arachidonic acid metabolism2WWP
FIGNL1Fidgetin-like protein 1Q6PIW4341-674ATPases – AAA3D8B
NVLNuclear valosin-containing protein-like O15381573-845ATPases – AAA2X8A
SPG7Paraplegin Q9UQ90305-565ATPases – AAA2QZ4
DDX10Probable ATP-dependent RNA helicaseQ1320647-280ATPases – DExD-DExH RNA helicases2PL3
DDX18ATP-dependent RNA helicaseQ9NVP1149-387ATPases – DExD-DExH RNA helicases3LY5
DDX19BATP-dependent RNA helicaseQ9UMR254-475ATPases – DExD-DExH RNA helicases3EWS/3G0H
DDX20Probable ATP-dependent RNA helicaseQ9UHI641-268ATPases – DExD-DExH RNA helicases2OXC/3B7G
DDX25ATP-dependent RNA helicaseQ9UHL0307-479ATPases – DExD-DExH RNA helicases2G2J/2RB4
DDX3XATP-dependent RNA helicaseO00571168-352ATPases – DExD-DExH RNA helicases2I4I
DDX41Probable ATP-dependent RNA helicase DDX41Q9UJV9402-569ATPases – DExD-DExH RNA helicases2P6N
DDX47Probable ATP-dependent RNA helicaseQ9H0S45-230ATPases – DExD-DExH RNA helicases3BER
DDX5Probable ATP-dependent RNA helicaseP1784468-307ATPases – DExD-DExH RNA helicases3FE2
DDX52Probable ATP-dependent RNA helicaseQ9Y2R4139-381ATPases – DExD-DExH RNA helicases3DKP
DDX53Probable ATP-dependent RNA helicaseQ86TM3204-430ATPases – DExD-DExH RNA helicases3IUY
DHX9ATP-dependent RNA helicase AQ08211329-563ATPases – DExD-DExH RNA helicases3LLM
EIF4A1Eukaryotic initiation factor 4A-IP6084220-238ATPases – DExD-DExH RNA helicases2G9N
IFIH1Interferon-induced helicase C domain-containing protein 1 Q9BYX4277-490ATPases – DExD-DExH RNA helicases3B6E
HSPA1AHeat shock 70 kDa protein 1A P0DMV81-387ATPases – Hsp703JXU
HSPA1LHeat shock 70 kDa protein 1-like P349311-386ATPases – Hsp703GDQ
HSPA2Heat shock-related 70 kDa protein 2 P546526-386ATPases – Hsp703I33
HSPA5Endoplasmic reticulum chaperone BiP P1102126-410ATPases – Hsp703IUC
HSPA6Heat shock 70 kDa protein 6 P170666-385ATPases – Hsp703FE1
HSPA9Stress-70 protein, mitochondrial P38646439-597ATPases – Hsp703N8E
BRDTBromodomain testis-specific proteinQ58F2121-137Bromodomain2RFJ
CECR2Chromatin remodeling regulator CECR2, bromodomain Q9BXF3424-538Bromodomain3NXB
CREBBPCREB-binding protein, bromodomain Q927931081-1197Bromodomain3P1D
EP300Histone acetyltransferase p300, bromodomain Q094721040-1161Bromodomain3I3J
KAT2AHistone acetyltransferase KAT2A, bromodomain Q92830729-837Bromodomain3D7C
KAT2BHistone acetyltransferase KAT2B, bromodomain Q92831715-831Bromodomain3GG3
PBRM1Protein polybromo-1, bromodomain Q86U8643-156Bromodomain3G0J
PBRM1Protein polybromo-1, bromodomain Q86U86178-291Bromodomain3HMF
PBRM1Protein polybromo-1, bromodomain Q86U86388-494Bromodomain3IU5
PBRM1Protein polybromo-1, bromodomain Q86U86645-766Bromodomain3IU6
PBRM1 Protein polybromo-1, bromodomain Q86U86773-917Bromodomain3K2J
PHIPPH-interacting protein, bromodomain 2 Q8WWQ01302-1434 Bromodomain3MB3
TAF1LTranscription initiation factor TFIID subunit 1-like, bromodomain Q8IZX41523-1654Bromodomain3HMH
BACH1Transcription regulator protein BACH1, BTB domain O148677-128BTB-Kelch2IHC
BTBD6BTB/POZ domain-containing protein 6Q96KE9129-236BTB-Kelch2VKP
GANGigaxonin, BTB domain Q9H2C06-126BTB-Kelch2PPI
KLHL11Kelch-like protein 11 Q9NVR067-340BTB-Kelch3I3N
KLHL12Kelch-like protein 12 Q53G59267-567BTB-Kelch2VPJ
KLHL2Kelch-like protein 2 O95198294-591BTB-Kelch2XN4
KLHL7Kelch-like protein 7 Q8IXQ5283-586BTB-Kelch3II7
MYNNMyoneurin, BTB domain Q9NPC74-117BTB-Kelch2VPK
ZBTB33Transcriptional regulator Kaiso, BTB domain Q86T241-116BTB-Kelch3FKC
ZBTB48Telomere zinc finger-associated protein, BTB domain P100744-120BTB-Kelch3B84
RADILRas-associating and dilute domain-containing protein, Ras association domain Q96JH851-193Cell-type specific expression – endothelial cell3EC8
GUCY1B1Guanylate cyclase 1, soluble, beta-1 Q02153408-619Cyclase-Nucleotide2WZ1
MACROD1ADP-ribose glycohydrolase MACROD1, MACRO domain Q9BQ6991-325Deacetyalases2X47
RECQLATP-dependent DNA helicase Q1P4606349-616DEAD-DNA-Helicase2V1X
ALDH1L1Cytosolic 10-formyltetrahydrofolate dehydrogenaseO758911-307Dehydrogenases & Reductases – Other DRs2BW0/2CFI
DPYSL2ᅠᅠᅠDihydropyrimidinase-related protein 2Q1655513-490Dehydrogenases & Reductases – Other DRs2GSE
DPYSᅠᅠᅠDihydropyrimidinaseQ141171-519Dehydrogenases & Reductases – Other DRs2VR2
CBLBE3 ubiquitin-protein ligase CBL-BQ1319138-344E3-Ligase3PFV
CBLCE3 ubiquitin-protein ligase CBL-CQ9ULV89-323E3-Ligase3OP0
CUL5Cullin-5Q9D5V51-386E3-Ligase2WZK
ERI3ERI1 exoribonuclease 3 O43414137-337Endo/Exo Nucleases2XRI
EXOGNuclease EXOG, mitochondrialQ9Y2C442-368Endo/Exo Nucleases4A1N
ASH1LHistone-lysine N-methyltransferase ASH1L, bromodomain Q9NR482438-2561Epigenetic targets: Bromodomains3MQM
BAZ2B Bromodomain adjacent to zinc finger domain protein 2B Q9UIF82054-2168Epigenetic targets: Bromodomains3G0L
BPTFNucleosome-remodeling factor subunit BPTF, bromodomain Q128302914-3037Epigenetic targets: Bromodomains
BRD1Bromodomain-containing protein 1 O95696 556-688Epigenetic targets: Bromodomains3RCW
BRD9 Bromodomain-containing protein 9 O95696134-239Epigenetic targets: Bromodomains3HME
BRWD1Bromodomain and WD repeat-containing protein 1, bromodomain 2 Q9NSI61310-1430 Bromodomain 2Epigenetic targets: Bromodomains3Q2E
MINABifunctional lysine-specific demethylase and histidyl-hydroxylase MINA Q8IUF826-465Epigenetic targets: Demethylases2XDV
RGS1Regulator of G-protein signalling 1 Q0811663-205G-protein-Regulator2BV1
RGS10Regulator of G-protein signalling 10 (isoform b)O4366530-165G-protein-Regulator2I59
RGS14Regulator of G-protein signalling 14 O4356656-207G-protein-Regulator2JNU
RGS16Regulator of G-protein signalling 16 O1549253-190G-protein-Regulator2BT2
RGS17Regulator of G-protein signalling 17 Q9UGC672-206G-protein-Regulator1ZV4
RGS18Regulator of G-protein signalling 18 Q9NS2875-223G-protein-Regulator2OWI
RGS2Regulator of G-protein signalling 2P4122071-203G-protein-Regulator2AF0
RGS3Regulator of G-protein signalling 3 (isoform 1), PDZ domain P49796299-384G-protein-Regulator2F5Y
RGS6Regulator of G-protein signalling 6 P49758325-470G-protein-Regulator2ES0
RGS7Regulator of G-protein signalling 7 P49802320-463G-protein-Regulator2A72
RGS8Regulator of G-protein signalling 8 P5777142-173G-protein-Regulator2IHD
ARHGAP15Rho GTPase-activating protein 15Q53QZ3262-473GTPase-GAP3BYI
RACGAP1Rac GTPase-activating protein 1 Q9H0H5348-546GTPase-GAP2OVJ
AGAP2Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, GTPase like domain Q99490402-577GTPase-RAS2IWR
DIRAS1GTP-binding protein Di-Ras1O950571-198GTPase-RAS2GF0
DIRAS2GTP-binding protein Di-Ras2Q96HU85-176GTPase-RAS2ERX
GEMGTP-binding protein GEMP5504062-249GTPase-RAS2G3Y
REM1GTP-binding protein REM 1O7562879-251GTPase-RAS2NZJ
RERGRas-related and estrogen-regulated growth inhibitorQ96A581-174GTPase-RAS2ATV
RRADGTP-binding protein RAD P5504287-260GTPase-RAS2GJS
RRASRas-related protein R-Ras P1030123-201GTPase-RAS2FN4
RRAS2Ras-related protein R-Ras2 P6207012-181GTPase-RAS2ERY
RAC3Ras-related C3 botulinum toxin substrate 3 P607631-192GTPase-RHO2C2H
RHOBRho-related GTP-binding protein RhoB P627454-184GTPase-RHO2FV8
RHODRho-related GTP-binding protein RhoD O002127-197GTPase-RHO2J1L
RHOURho-related GTP-binding protein RhoU Q7L0Q832-230GTPase-RHO2Q3H
RND1Rho-related GTP-binding protein Rho6 Q927305-200GTPase-RHO2CLS
ADAAdenosine deaminaseP008135-363Hydrolase-Other3IAR
ECH1Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrialQ1301139-49,50-322Hydrolase-Other2VRE
ECHDC3Enoyl-CoA hydratase domain-containing protein 3, mitochondrialQ96DC837-300Hydrolase-Other2VX2
ECHS1Enoyl-CoA hydratase, mitochondrialP3008428-290Hydrolase-Other2HW5
ERAP1Endoplasmic reticulum aminopeptidase 1Q9NZ081-505Hydrolase-Other2XDT
FHFumarate hydratase, mitochondrialP0795444-510Hydrolase-Other3E04
HDHD2Haloacid dehalogenase-like hydrolase domaing-containing 2Q9H0R41-259Hydrolase-Other3HLT
HDHD3Haloacid dehalogenase-like hydrolase domain-containing 3Q9BSH58-247Hydrolase-Other3K1Z
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrialQ6NVY132-386Hydrolase-Other3BPT
MDP1Magnesium-dependent phosphatase 1 Q86V881-165Hydrolase-Other2WM8
PTS6-pyruvoyltetrahydropterin synthase Q033937-145Hydrolase-Other3I2B
PUDPPseudouridine-5′-phosphatase Q086231-228Hydrolase-Other3L5K
ECI2Enoyl-CoA delta isomerase 2 O75521137-394Isomerase2F6Q
MMUTMethylmalonyl-CoA mutase, mitochondrial P2203312-750Isomerase3BIC
AKT3RAC-gamma serine/threonine-protein kinaseQ9Y2431-118Kinase-AGC2X18
DMPKMyotonin-protein kinase Q0901310-420Kinase-AGC2VD5
MAST1Microtubule associated serine/threonine kinase 1, PDZ domain Q9Y2H9965-1057Kinase-AGC3PS4
MAST3Microtubule associated serine/threonine kinase 3, PDZdomain O60307948-1040Kinase-AGC3KHF
MAST4Microtubule-associated serine/threonine-protein kinase 4 , PDZ domain O150211140-1231Kinase-AGC2W7R
PRKCGProtein kinase C gamma type, C2 domain P05129154-295Kinase-AGC2UZP
RPS6KA1Ribosomal protein S6 kinase alpha-1 Q15418404-719Kinase-AGC2WNT
CAMK1DCalcium/calmodulin-dependent protein kinase type 1D Q8IU851-333Kinase-CAMK2JC6
CAMK1GCalcium/calmodulin-dependent protein kinase type 1G Q96NX518-316Kinase-CAMK2JAM
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha Q9UQM713-302Kinase-CAMK2VZ6
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit betaQ1355411-303Kinase-CAMK3BHH
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta Q1355711-309Kinase-CAMK2VN9
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta Q13557334-475Kinase-CAMK2W2C
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma Q135555-315Kinase-CAMK2V7O
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma Q13555425-558Kinase-CAMK2UX0
CAMK4Calcium/calmodulin-dependent protein kinase type IV Q1656615-340Kinase-CAMK2W4O
MYLK4Myosin light chain kinase family, member 4 Q86YV640-388Kinase-CAMK2X4F
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform P157356-293Kinase-CAMK2Y7J
PIM2Serine/threonine-protein kinase Q9P1W91-311Kinase-CAMK2IWI
CSNK1G1 Casein kinase I isoform gamma-1 P7836845-352Kinase-CK12CMW
CSNK1G2 Casein kinase I isoform gamma-2 Q9HCP043-353Kinase-CK12C47
CSNK1G3Casein kinase I isoform gamma-3 Q9Y6M435-362Kinase-CK12IZR
VRK1Serine/threonine-protein kinase VRK1, protein kinase domain Q999863-364Kinase-CK13OP5
VRK2Serine/threonine-protein kinase VRK2, protein kinase domain Q86Y0714-335Kinase-CK12V62
VRK3Serine/threonine-protein kinase VRK3, protein kinase domain Q8IV63138-474Kinase-CK12JII
CLK1Dual specificity protein kinase CLK1 P49759148-484Kinase-CMGC1Z57
CLK2Dual specificity protein kinase CLK2 P49760135-496Kinase-CMGC3NR9
DYRK2Dual specificity tyrosine-phosphorylation-regulated kinase 2 Q92630146-552Kinase-CMGC3K2L
MAPK11Mitogen-activated protein kinase 11 (p38b)Q157595-350Kinase-CMGC3GP0
MAPK6Mitogen-activated protein kinase 6 Q166599-327Kinase-CMGC2I6L
PCTK1Cyclin-dependent kinase 16 Q00536163-478Kinase-CMGC3MTL
SRPK2SFRS protein kinase 2 P7836250-688Kinase-CMGC2X7G
GAKCyclin-G-associated kinase O1497612-347Kinase-Other3LL6
PTK2B Protein-tyrosine kinase 2-beta Q14289414-692Kinase-Other3CC6
STK16Serine/threonine protein kinase 16 O7571613-305Kinase-Other2BUJ
TTKDual specificity protein kinase TTK P33981519-808Kinase-Other3CEK
ITPK1Inositol-tetrakisphosphate 1-kinase Q135721-327Kinase-PIK2ODT
ITPKCInositol-trisphosphate 3-kinase C Q96DU7425-683Kinase-PIK2A98
PIK3C2GPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma, PX domain O757471198-1307Kinase-PIK2WWE
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3 Q8NEB9282-879Kinase-PIK3IHY
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3 Q8NEB9268-879Kinase-PIK3LS8
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit betaO00459108-298Kinase-PIK2XS6
PIP5K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Q8TBX832-421Kinase-PIK2GK9
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6 P5256447-334Kinase-STE3FME
MAP3K3Mitogen-activated protein kinase kinase kinase 3 (isoform 2) PB1 domain Q9975927-124Kinase-STE2C60
MAP3K5Mitogen-activated protein kinase kinase kinase 5 (MAPK/ERK kinase kinase 5)Q99683659-951Kinase-STE2CLQ
PAK4Serine/threonine-protein kinase PAK 4 O96013291-591Kinase-STE2Q0N
PAK5Serine/threonine-protein kinase PAK 5 Q9P286425-719Kinase-STE2F57
PAK6Serine/threonine-protein kinase PAK 6 Q9NQU5383-681Kinase-STE2C30
SLKSTE20-like serine/threonine-protein kinase Q9H2G212-15,16-320Kinase-STE2UV2
STK25Serine/threonine-protein kinase 25 O005061-293Kinase-STE2XIK
STK26Serine/threonine-protein kinase 26 Q9P2891-300Kinase-STE3GGF
TNIKTRAF2 and NCK interacting protein kinase Q9UKE51-325Kinase-STE2X7F
ABL2Tyrosine-protein kinase ABL2P42684279-546Kinase-TK3GVU
FESTyrosine-protein kinase Fes/Fps P07332448-822Kinase-TK3BKB
FLT1Vascular endothelial growth factor receptor 1 P17948801-1158Kinase-TK and PARP domain?3HNG
ACVR1Activin receptor type-1Q04771201-499Kinase-TKL3MTF
ACVR2AActivin receptor type-2AP27037191-488Kinase-TKL3SOC
ACVRL1Serine/threonine-protein kinase receptor R3P37023195-497Kinase-TKL3MY0
LIMK1LIM domain kinase 1 (isoform 1), kinase domain P53667330-637Kinase-TKL3S95
MAP3K10Mitogen-activated protein kinase kinase kinase 10, SH3 domains Q0277913-78Kinase-TKL2RF0
ROR2Tyrosine-protein kinase transmembrane receptor ROR2 Q01974463-751Kinase-Tyr3ZZW
AK1Adenylate kinase isoenzyme 1 P005681-193Kinases2C95
AK2 Adenylate kinase isoenzyme 2, mitochondrial P548191-239Kinases2C9Y
AK4Adenylate kinase isoenzyme 4, mitochondrial P271441-223Kinases2BBW
AK5Adenylate kinase isoenzyme 5 Q9Y6K8366-562Kinases2BWJ
BMPR2Bone morphogenetic protein receptor type-2 Q13873189-517Kinases3G2F
HASPINSerine/threonine-protein kinase haspin Q8TF76465-798Kinases
MPSK1Serine/threonine-protein kinase 16 O7571613-305Kinases
MST4Serine/threonine-protein kinase Q9P2891-300Kinases
NEK2Serine/threonine-protein kinase P519551-271Kinases2JAV
ACACAAcetyl-CoA carboxylase 1Q1308578-617Ligase2YL2
PCCAPropionyl-Coenzyme A carboxylase, alpha polypeptide precursor P05165658-728Ligase2JKU
ACSM2AAcyl-coenzyme A synthetase ACSM2A, mitochondrialQ08AH332-577Ligase AMP-Binding3C5E
DLG2Discs, large homolog 2, second PDZ domain Q15700418-513Linker-PDZ2HE2
DLG2Discs, large homolog 2, first PDZ domain Q15700190-283Linker-PDZ2BYG
DLG3Discs, large homolog 3 first PDZ domain Q92796126-222Linker-PDZ2I1N
DLG3Discs, large homolog 3 second PDZ domain Q92796223-314Linker-PDZ2FE5
DVL2Segment polarity protein dishevelled homolog DVL-2, PDZ domain O14641261-355Linker-PDZ2REY
GIPC2PDZ domain-containing protein GIPC2 Q8TF65112-200Linker-PDZ3GGE
GRIP1Glutamate receptor interacting protein 1, 2nd PDZ domain Q9Y3R0148-239Linker-PDZ2JIL
LNX1E3 ubiquitin-protein ligase LNX, PDZ domain Q8TBB1504-594Linker-PDZ3B76
LNX2Ligand of Numb protein X 2, PDZ domain Q8N448336-425Linker-PDZ2VWR
MAGI1Membrane associated guanylate kinase WW and PDZ containing protein 1, 4th PDZ domain Q96QZ7839-922Linker-PDZ2Q9V
MAGI1Membrane associated guanylate kinase WW and PDZ containing protein 1, 6th PDZ domain containing C1190S mutant Q96QZ71149-1233Linker-PDZ2R4H
MAGI1Membrane associated guanylate kinase WW and PDZ containing protein 1, 3th PDZ domain continaing double mutant, C677S and C709S Q96QZ7640-721Linker-PDZ3BPU
MPDZMultiple PDZ domain protein, 1st PDZ domain O75970117-227Linker-PDZ2O2T
MPDZMultiple PDZ domain protein, 3rd PDZ domain O75970373-463Linker-PDZ2IWN
MPDZMultiple PDZ domain protein, 7th PDZ domain O759701148-1243Linker-PDZ2FCF
MPDZMultiple PDZ domain protein, 12th PDZ domain O759701858-1951Linker-PDZ2IWO
MPDZMultiple PDZ domain protein, 13th PDZ domain O759701983-2070Linker-PDZ2FNE
MPDZMultiple PDZ domain protein, 10th PDZ domain O759701625-1716Linker-PDZ2OPG
MPDZMultiple PDZ domain protein, 11th PDZ domain O759701722-1806Linker-PDZ2QG1
NHERF1Na(+)/H(+) exchange regulatory cofactor NHE-RF1, PDZ domain O14745150-235Linker-PDZ2OZF
NHERF2Na(+)/H(+) exchange regulatory cofactor NHE-RF2, PDZ domain Q15599147-230Linker-PDZ2HE4
NHERF2Na(+)/H(+) exchange regulatory cofactor NHE-RF2, PDZ domain Q155999-91Linker-PDZ2OCS
NHERF4Na(+)/H(+) exchange regulatory cofactor NHE-RF4, PDZ domain Q86UT5326-419Linker-PDZ2V90
PDLIM1PDZ and LIM domain protein 1, PDZ domain O001511-87Linker-PDZ2PKT
PDLIM2PDZ and LIM domain protein 2, PDZ domain Q96JY61-82Linker-PDZ2PA1
PDLIM4PDZ and LIM domain protein 4, PDZ domain P504791-87Linker-PDZ2V1W
PDLIM5PDZ and LIM domain protein 5, PDZ domain Q96HC41-85Linker-PDZ2UZC
PDLIM7PDZ and LIM domain protein 7, PDZ domain Q9NR121-84Linker-PDZ2Q3G
PDZK1Na(+)/H(+) exchange regulatory cofactor NHE-RF3, PDZ domain Q5T2W1375-461Linker-PDZ2VSP
PICK1RKCA-binding protein, PDZ domain Q9NRD518-105Linker-PDZ2GZV
RHPN2Rhophilin-2, PDZ domain Q8IUC4514-598Linker-PDZ2VSV
SCRIBProtein scribble homolog, PDZ domain Q14160725-815Linker-PDZ2W4F
SNTB2Beta-2-syntrophin, PDZ domain Q13425112-200Linker-PDZ2VRF
SYNJ2BPSynaptojanin 2 binding protein, PDZ domain P571055-101Linker-PDZ2JIK
TAMALINGRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, PDZ domain Q7Z6J297-192Linker-PDZ2PNT
TAX1BP3Tax1-binding protein 3, PDZ domain O1490711-124Linker-PDZ2VZ5
ACOT11Acyl-coenzyme A thioesterase 11, START domain Q8WXI4339-543Lipid signalling-Other3FO5
ACOT12Acyl-coenzyme A thioesteraseQ8WYK07-316Lipid signalling-Other3B7K
ACOT4Peroxisomal succinyl-coenzyme A thioesteraseQ8N9L91-421Lipid signalling-Other3K2I
ACOT7Cytosolic acyl coenzyme A thioester hydrolaseO00154209-378Lipid signalling-Other2QQ2
bphA4Biphenyl dioxygenase ferredoxin reductase subunit E7FJB91-408Lipid signalling-Other2H4U
EPB41L3Band 4.1-like protein 3, FERM domain Q9Y2J2108-390Lipid signalling-Other2HE7/3BIN
FABP1Fatty acid-binding protein, liverP071481-127Lipid signalling-Other2F73
STARD13StAR-related lipid transfer protein 13, START domain Q9Y3M8903-1113Lipid signalling-Other2PSO
STARD5StAR-related lipid transfer protein 5, START domain QN9SY26-213Lipid signalling-Other2R55
LCN15Lipocalin-15 Q6UWW019-177Lipocalin2XST
PMP2Myelin P2 protein P026893-132Lipocalin3NR3
CA13Carbonic anhydrase 13Q8N1Q11-261Lyase-Carbonic-Anhydrase3DA2
CA6Carbonic anhydrase 6P2328020-290Lyase-Carbonic-Anhydrase3FE4
CA7Carbonic anhydrase 7P431665-262Lyase-Carbonic-Anhydrase3MDZ
CA8Carbonic anhydrase-related proteinP352191-290Lyase-Carbonic-Anhydrase2W2J
HTD2Hydroxyacyl-thioester dehydratase type 2, mitochondrial P8639723-168Lyase-Other3IR3
MLYCDMalonyl-CoA decarboxylase O9582240-490Lyase-Other2YGW
MAGEA4Melanoma antigen family A, 4 P4335899-317MAGE2WA0
RAMP2Receptor activity-modifying protein 2 O6089548-139Membrane-GPCR2XVT
GHRHRGrowth hormone-releasing hormone receptorQ0264334-123Membrane-GPCR-ECD2XDG
VIPR2Vasoactive intestinal polypeptide receptor 2, hormone receptor domain P4158726-118Membrane-GPCR-ECD2X57
ELAC1Zinc phosphodiesterase ELAC protein 1Q9H7773-363Metallo-Beta-Lactamase? Zinc phosphodiesterase3ZWF
HSP90B1Heat shock protein HSP 90-betaP08238284-543Miscellaneous3PRY
MMACHCCyanocobalamin reductase or alkylcobalamin dealkylase Q9Y4U11-282Miscellaneous3SOM
TATDN1Deoxyribonuclease TATDN1 Q6P1N95-295Miscellaneous2XIO
TATDN3Putative deoxyribonuclease TATDN3 Q17R315-274Miscellaneous2Y1H
TP73Tumor protein p73 O15350112-311Miscellaneous2XWC
NUMBLNumb-like protein Q9Y6R060-204Neuronal stem cell development3F0W
THTyrosine 3-monooxygenase P07101193-528Neurotransmitter-Synthesis2XSN
ADAT2tRNA-specific adenosine deaminase 2Q7Z6V520-185Nucleotide metabolism-Deaminases3DH1
GDAᅠᅠᅠGuanine deaminaseQ9Y2T31-454Nucleotide metabolism-Deaminases2UZ9
ITPKBInosine triphosphate pyrophosphataseQ9BY321-194Nucleotide metabolism-Nucleotide phosphatases2CAR/2J4E
RRM1Ribonucleoside-diphosphate reductase large subunit P2392175-742Nucleotide metabolism-Nucleotide reductases2WGH
RRM2Ribonucleoside-diphosphate reductase subunit M2 P3135060-389Nucleotide metabolism-Nucleotide reductases2UW2
RRM2BRibonucleoside-diphosphate reductase subunit M2 B Q7LG5617-322Nucleotide metabolism-Nucleotide reductases2VUX
NUDT1Oxidized purine nucleoside triphosphate hydrolaseP366391-156Nucleotide metabolism-NUDIX3Q93
NUDT10Diphosphoinositol polyphosphate phosphohydrolase 3-alpha Q8NFP717-144Nucleotide metabolism-NUDIX3MCF
NUDT14 Uridine diphosphate glucose pyrophosphatase O9584828-222Nucleotide metabolism-NUDIX3Q91
NUDT16 U8 snoRNA-decapping enzyme Q96DE01-195Nucleotide metabolism-NUDIX3COU/’2XSQ
NUDT16L1 Protein syndesmos Q9BRJ76-211Nucleotide metabolism-NUDIX3KVH
NUDT18 8-oxo-dGDP phosphatase NUDT18 Q6ZVK8 26-179Nucleotide metabolism-NUDIX3GG6
NUDT21Cleavage and polyadenylation specificity factor subunit 5 O4380919-227Nucleotide metabolism-NUDIX2CL3
NUDT21Cleavage and polyadenylation specificity factor subunit 5 O4380920-227Nucleotide metabolism-NUDIX2J8Q
NUDT6 Nucleoside diphosphate-linked moiety X motif 6 P53370141-316Nucleotide metabolism-NUDIX3FXT
ADSLᅠᅠᅠAdenylosuccinate lyase P305661-481Nucleotide metabolism-Others2J91/2VD6
ADSS2Adenylosuccinate synthetase isozyme 2P3052021-456Nucleotide metabolism-Others2V40
CTPS1CTP synthase 1, synthase domain P178121-273Nucleotide metabolism-Others2C5M/2VO1
CTPS2CTP synthase 2, glutaminase domain Q9NRF8292-562Nucleotide metabolism-Others2V4U/2VKT
CTPS2CTP synthase 2, synthase domain Q9NRF81-275Nucleotide metabolism-Others3IHL
DCTDᅠᅠᅠDeoxycytidylate deaminaseP323214-174Nucleotide metabolism-Others2W4L
GARTTrifunctional purine biosynthetic protein adenosine-3 P221021-430Nucleotide metabolism-Others2QK4
GART Trifunctional purine biosynthetic protein adenosine-3 P22102467-794Nucleotide metabolism-Others2V9Y
GMPSGMP synthetase [glutamine hydrolyzing], glutaminase domain P4991511-219Nucleotide metabolism-Others2VPI
GMPSGMP synthetase [glutamine hydrolyzing] P4991520-693Nucleotide metabolism-Others2VXO
PRPSAP1ᅠᅠᅠPhosphoribosyl pyrophosphate synthase-associated protein 1Q145581-351Nucleotide metabolism-Others2C4K
PRPSAP2Phosphoribosyl pyrophosphate synthase-associated protein 2O6025612-369Nucleotide metabolism-Others2JI4
PRTFDC1Phosphoribosyltransferase domain-containing protein 1Q9NRG11-225Nucleotide metabolism-Others2JBH
UCK1Uridine-cytidine kinase 1 Q9HA4721-243Nucleotide metabolism-Others2JEO/2UVQ
UMPSUridine 5′-monophosphate synthase P11172224-479Nucleotide metabolism-Others2JGY/2V30
UMPSUridine 5′-monophosphate synthase P111727-203Nucleotide metabolism-Others2WNS
UPP2Uridine phosphorylase 2 O9504523-317Nucleotide metabolism-Others2XRF
CCNT2Cyclin-T2O605837-263Other-Cyclin2IVX
ACBD4Acyl-CoA-binding domain-containing protein 4Q8NC067-110Other-NonDR2WH5
ACBD5Acyl-CoA-binding domain-containing protein 5Q5T8D341-136Other-NonDR3FLV
ACBD7Acyl-CoA-binding domain-containing protein 7Q8N6N71-88Other-NonDR3EPY
CRYBA4Beta-crystallin A4P536738-196Other-NonDR3LWK
CRYBB3Beta-crystallin B3P2699821-199Other-NonDR3QK3
FDX1Adrenodoxin, mitochondrialP1010961-184Other-NonDR3P1M
GMFGGlia maturation factor gammaO602347-140Other-NonDR3L50
LHPPPhospholysine phosphohistidine inorganic pyrophosphate phosphataseQ9H0081-270Other-NonDR2X4D
MMAAMethylmalonic aciduria type A protein, mitocondrial Q8IVH470-418Other-NonDR2WWW
TTC5Tetratricopeptide repeat protein 5 Q8N0Z6261-424Other-Signal2XVS
TWF2Twinfilin-2 Q6IBS06-137Other-Signal2VAC
TWF2Twinfilin-2 Q6IBS0179-313Other-Signal2W0I
YWHAB14-3-3 protein beta/alpha P319461-240Other-Signal2BQ0
YWHAE14-3-3 protein epsilon P622581-233Other-Signal2BR9
YWHAG14-3-3 protein gamma P619812-247Other-Signal2B05
YWHAH14-3-3 protein eta Q049171-246Other-Signal2C74
YWHAQ14-3-3 protein theta P273481-234Other-Signal2BTP
ASPHAspartyl/asparaginyl beta-hydroxylaseQ12797562-758Oxidoreductase-2OG3RCQ
BBOX1Gamma-butyrobetaine dioxygenaseO759361-387Oxidoreductase-2OG3MS5
JMJD6Bifunctional arginine demethylase and lysyl-hydroxylase Q6NYC12-335Oxidoreductase-2OG3K2O
KDM4ALysine-specific demethylase 4A O751641-359Oxidoreductase-2OG2OQ7
KDM4CLysine-specific demethylase 4C Q9H3R0875-995Oxidoreductase-2OG2XDP
KDM4ELysine-specific demethylase 4EB2RXH21-336Oxidoreductase-2OG2W2I
KDM5CLysine-specific demethylase 5CP4122973-188Oxidoreductase-2OG2JRZ
KDM6BLysine-specific demethylase 6B O150541176-1505Oxidoreductase-2OG2XXZ
PHF8Histone lysine demethylase PHF8 Q9UPP1115-483Oxidoreductase-2OG2WWU
PHYHD1hytanoyl-CoA dioxygenase domain-containing protein 1 Q5SRE71-291Oxidoreductase-2OG2OPW
ACAD11Acyl-CoA dehydrogenase family member 11Q709F0353-780Oxidoreductase-Acyl-CoA2WBI
ACADSShort-chain specific acyl-CoA dehydrogenase, mitochondrialP1621930-412Oxidoreductase-Acyl-CoA2VIG
ACADSBShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialP4595452-432Oxidoreductase-Acyl-CoA2JIF
ACADVLVery long-chain specific acyl-CoA dehydrogenase, mitochondrialP4974869-655Oxidoreductase-Acyl-CoA2UXW
AKR1C4Aldo-keto reductase family 1 member C4 P175161-323Oxidoreductase-AKR2FVL
AKR7A2Aflatoxin B1 aldehyde reductase member 2 O434881-359Oxidoreductase-AKR2BP1
AKR7A3Aflatoxin B1 aldehyde reductase member 3 O951546-331Oxidoreductase-AKR2CLP
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase P54886362-795Oxidoreductase-ALDH2H5G
ALDH7A1Alpha-aminoadipic semialdehyde dehydrogenase P4941929-527Oxidoreductase-ALDH2J6L
GPX1Glutathione peroxidase 1P0720314-198Oxidoreductase-GPX2F8A
GPX2Glutathione peroxidase 2P182834-188Oxidoreductase-GPX2HE3
GPX3Glutathione peroxidase 3P2235225-223Oxidoreductase-GPX2R37
GPX4Glutathione peroxidase 4P3696936-197Oxidoreductase-GPX2GS3
GPX5Epididymal secretory glutathione peroxidaseO7571528-220Oxidoreductase-GPX2I3Y
GPX7Glutathione peroxidase 7Q96SL420-177Oxidoreductase-GPX2P31
GPX8Probable glutathione peroxidase 8Q8TED144-209Oxidoreductase-GPX3CYN
ADH4All-trans-retinol dehydrogenase [NAD(+)] ADH4 P083191-380Oxidoreductase-MDR3COS
FASNFatty acid synthaseP49327422-831Oxidoreductase-MDR2JFK
MECREnoyl-[acyl-carrier-protein] reductase, mitochondrial Q9BV7940-373Oxidoreductase-MDR1ZSY
PTGR1Prostaglandin reductase 1Q149144-329Oxidoreductase-MDR1ZSV
PTGR2Prostaglandin reductase 2Q8N8N71-350Oxidoreductase-MDR2VNA
PTGR3Prostaglandin reductase 3 Q8N4Q033-371Oxidoreductase-MDR2C0C
PTGR3Prostaglandin reductase 3 Q8N4Q031-370Oxidoreductase-MDR2WEK
RTN4IP1Reticulon-4-interacting protein 1, mitochondrial Q8WWV345-396Oxidoreductase-MDR2VN8
TP53I3Quinone oxidoreductase PIG3Q53FA71-332Oxidoreductase-MDR2J8Z
BLVRABiliverdin reductase AP530047-296Oxidoreductase-Other2H63
CRYL1Lambda-crystallin homologQ9Y2S26-316Oxidoreductase-Other3F3S
CTBP2C-terminal binding protein 2P5654531-364Oxidoreductase-Other2OME
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase, testis-specificO1455669-407Oxidoreductase-Other3H9E
GLOD5Glyoxalase domain-containing protein 5 A6NK4434-157Oxidoreductase-Other3ZW5
GLRX2Glutaredoxin-2, mitochondrial Q9NS1841-164Oxidoreductase-Other2HT9
GLRX2Glutaredoxin-2, mitochondrial Q9NS1856-164Oxidoreductase-Other2FLS
GLRX3Glutaredoxin-3 O760031-134Oxidoreductase-Other2WZ9
GLRX3Glutaredoxin-3 O76003232-334Oxidoreductase-Other2YAN
GLYR1Cytokine-like nuclear factor N-PACQ49A26261-553Oxidoreductase-Other2UYY
GMPRGMP reducatse 1P369591-345Oxidoreductase-Other2BLE
GPD1LGlycerol-3-phosphate dehydrogenase 1-like proteinQ8N3351-349Oxidoreductase-Other2PLA
HAO12-Hydroxyacid oxidase 1Q9UJM81-370Oxidoreductase-Other2NZL
HIBADH3-Hydroxyisobutyrate dehydrogenase, mitochondrialP3193741-335Oxidoreductase-Other2GF2
HPD4-hydroxyphenylpyruvate dioxygenaseP327548-393Oxidoreductase-Other3ISQ
MCEEMethylmalonyl CoA epimerase Q96PE745-176Oxidoreductase-Other3RMU
MDH2Malate dehydrogenase 2, NAD (mitochondrial)P4092619-338Oxidoreductase-Other2DFD
ME1NADP-dependent malic enzyme P4816313-564Oxidoreductase-Other2AW5
MSRB1Methionine-R-sulfoxide reductase B1 Q9NZV610-112Oxidoreductase-Other3MAO
PGD6-phosphogluconate dehydrogenase, decarboxylating P522091-483Oxidoreductase-Other2JKV
PHGDHD-3-phosphoglycerate dehydrogenase O431754-314Oxidoreductase-Other2G76
PRDX4Peroxiredoxin 4 Q1316284-271Oxidoreductase-Other2PN8
PYCR1Pyrroline-5-carboxylate reductase 1, mitochondrialP323221-300Oxidoreductase-Other2IZZ
TXNRD1Thioredoxin reductase 1, cytoplasmic Q16881150-649Oxidoreductase-Other2CFY
TXNRD3Thioredoxin reductase 3 Q86VQ651-156Oxidoreductase-Other3H8Q
UGDHUDP-glucose 6-dehydrogenase O607011-466Oxidoreductase-Other2Q3E
BDH2Dehydrogenase/reductase SDR family member 6Q9BUT11-245Oxidoreductase-SDR2AG5
CBR3Carbonyl reductase [NADPH] 3O758286-277Oxidoreductase-SDR2HRB
DHRS1Dehydrogenase/reductase SDR family member 1Q96LJ73-262Oxidoreductase-SDR2QQ5
DHRS11Dehydrogenase/reductase SDR family member 11 Q6UWP21-256Oxidoreductase-SDR1XG5
DHRS4Dehydrogenase/reductase SDR family member 4Q9BTZ219-278Oxidoreductase-SDR3O4R
GMDSGDP-mannose 4,6-dehydrataseO6054723-372Oxidoreductase-SDR1T2A
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)]P154283-256Oxidoreductase-SDR2GDZ
HSD11B111-Beta-hydroxysteroid dehydrogenase 1P2884520-284Oxidoreductase-SDR2BEL
HSD17B103-hydroxyacyl-CoA dehydrogenase type-2Q997141-261Oxidoreductase-SDR2O23
HSD17B11Estradiol 17-beta-dehydrogenase 11Q8NBQ515-275Oxidoreductase-SDR1YB1
HSD17B1417-Beta-hydroxysteroid dehydrogenase 14Q9BPX11-270Oxidoreductase-SDR1YDE
HSD17B4Peroxisomal multifunctional enzyme type 2P516591-304Oxidoreductase-SDR1ZBQ
HSD17B8(3R)-3-hydroxyacyl-CoA dehydrogenaseQ925066-261Oxidoreductase-SDR2PD6
MAT2BMAT2B: methionine adenosyltransferase II, beta [RefSeq, isoform 2] (aka TGR, MAT-II, MGC12237, MATIIbeta, Nbla02999)Q9NZL928-334Oxidoreductase-SDR2YDX
NMRAL1NmrA-like family domain containing protein 1 Q9HBL81-298Oxidoreductase-SDR2WMD
PECRPeroxisomal trans-2-enoyl-CoA reductase Q9BY491-303Oxidoreductase-SDR1YXM
SPRSepiapterin reductase P352705-261Oxidoreductase-SDR1Z6Z
UXS1UDP-glucuronic acid decarboxylase 1 Q8NBZ785-402Oxidoreductase-SDR2B69
PARP10Protein mono-ADP-ribosyltransferase PARP10 Q53GL7809-1017PARP3HKV
PARP12Protein mono-ADP-ribosyltransferase PARP12 Q9H0J9489-684PARP2PQF
PARP14 Protein mono-ADP-ribosyltransferase PARP14 Q460N51611-1801PARP3GOY
PARP15 Protein mono-ADP-ribosyltransferase PARP15 Q460N3459-656PARP3BLJ/3GEY
PARP2Poly [ADP-ribose] polymerase 2 Q9UGN5235-579PARP3KCZ/3KJD
PARP3Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1178-532PARP2PA9/3C49/3C4H/3CE0/3FHB
TNKS1Poly [ADP-ribose] polymerase tankyrase-1 O952711091-1325PARP2RF5
TNKS2Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2946-1162PARP3KR7/3P0Q/3P0P/3KR8/3MHJ/3P0N
TNKS2Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2955-1162PARP3MHK
ZC3HAV1Zinc finger CCCH-type antiviral protein 1 Q7Z2W4724-896PARP2X5Y
PARP14Protein mono-ADP-ribosyltransferase Q460N5999-1196PARP domain3Q71
PARP14Protein mono-ADP-ribosyltransferase Q460N5789-979PARP domain3Q6Z
pcpPyrrolidone-carboxylate peptidaseQ5HCK71-212Pathogen3G1U
ProcessedCTP synthase Q4GZ95319-589Pathogen2W7T
TRYB2Adenosylhomocysteinase Q383X04-437Pathogen3H9U
ANLNAnillinQ9NQW6980-1113PH-Domain2Y7B
CDC25CM-phase inducer phosphatase 3 P30307270-462Phosphatase-Dual-Spec3OP3
DUSP13Dual specificity protein phosphatase 13B Q9UII61-198Phosphatase-Dual-Spec2PQ5
DUSP16Dual specificity protein phosphatase 16 Q9BY845-150Phosphatase-Dual-Spec2VSW
PGAM5Serine/threonine-protein phosphatase, mitochondrial Q96HS190-289Phosphatase-Dual-Spec3MXO
RNGTTmRNA-capping enzyme O609421-219Phosphatase-Other2C46
PTPRB Receptor-type tyrosine-protein phosphatase beta P234671686-1971Phosphatase-Tyr-Receptor2AHS
PTPRE Receptor-type tyrosine-protein phosphatase epsilon P23469107-697)Phosphatase-Tyr-Receptor2JJD
PTPRGReceptor-type tyrosine-protein phosphatase epsilon P23470827-1445Phosphatase-Tyr-Receptor2NLK
PTPRJReceptor-type tyrosine-protein phosphatase eta Q129131019-1311Phosphatase-Tyr-Receptor2H4V
PTPRJReceptor-type tyrosine-protein phosphatase etaQ129131016-1311Phosphatase-Tyr-Receptor2CFV
PTPRKReceptor-type tyrosine-protein phosphatase eta Q15262865-1154Phosphatase-Tyr-Receptor2NZ6
PTPRKReceptor-type tyrosine-protein phosphatase kappaQ15262853-1154Phosphatase-Tyr-Receptor2C7S
PTPRN2Receptor-type tyrosine-protein phosphatase N2 Q92932715-1010Phosphatase-Tyr-Receptor2QEP
PTPROReceptor-type tyrosine-protein phosphatase O Q16827916-1208Phosphatase-Tyr-Receptor2GJT
PTPRRReceptor-type tyrosine-protein phosphatase R Q15256375-655Phosphatase-Tyr-Receptor2A8B
PTPRT Receptor-type tyrosine-protein phosphatase T O14522868-1151Phosphatase-Tyr-Receptor2OOQ
PTPN11Tyrosine-protein phosphatase, non-receptor type 11 Q06124237-529Phosphatase-Tyr-Soluble3B7O
PTPN14Tyrosine-protein phosphatase non-receptortype 14 Q15678886-1187Phosphatase-Tyr-Soluble2BZL
PTPN18Tyrosine-protein phosphatase non-receptor type 18 Q999526-299Phosphatase-Tyr-Soluble2OC3
PTPN22Tyrosine-protein phosphatase non-receptor type 22Q9Y2R21-302Phosphatase-Tyr-Soluble2P6X
PTPN3Tyrosine-protein phosphatase non-receptor type 3 P26045628-913Phosphatase-Tyr-Soluble2B49
PTPN4Tyrosine-protein phosphatase non-receptor type 4 P29074611-926Phosphatase-Tyr-Soluble2I75
PTPN4Tyrosine-protein phosphatase non-receptor type 4, PDZ domain P29074513-610Phosphatase-Tyr-Soluble2VPH
PTPN5Tyrosine-protein phosphatase non-receptor type 5P54829277-563Phosphatase-Tyr-Soluble2CJZ
PTPN5Tyrosine-protein phosphatase non-receptor type 5P54829282-563Phosphatase-Tyr-Soluble2BV5
PTPN7Tyrosine-protein phosphatase non-receptor type 7 P3523665-358Phosphatase-Tyr-Soluble2A3K
PTPN9Tyrosine-protein phosphatase non-receptor type 9 P43378 277-582Phosphatase-Tyr-Soluble2PA5
MTMR6Myotubularin-related protein 6 Q9Y2171-505Phosphatases
NANPN-acylneuraminate-9-phosphatase Q8TBE91-248Phosphatases2W4M
MTMR6Myotubularin-related protein 6 Q9Y2171-507Phosphatases – Other2YF0
PHPT114 kDa phosphohistidine phosphatase Q9NRX45-125Phosphatases – Other2HW4
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Q1336211-380Phosphatases – Other2JAK
PTPASerine/threonine-protein phosphatase 2A activator Q1525722-358Phosphatases – Other2G62
THTPAThiamine-triphosphatase Q9BU021-215Phosphatases – Other3BHD
NISCHNischarin, PX-domain Q9Y2I118-124Phosphoinositide dependent signalling – Lipid binding domains3P0C
SNX7Sorting nexin-7, Pxdomain Q9UNH625-154Phosphoinositide dependent signalling – Lipid binding domains3IQ2
TULP1Tubby-related protein 1, Tub family domainO00294290-542Phosphoinositide dependent signalling – Lipid binding domains2FIM/3C5N
NUDT3Diphosphoinositol polyphosphate phosphohydrolase 1 O959891-172Phosphoinositide dependent signalling – Lipid phosphatases2FVV/2Q9P
MIOXInositol oxygenase Q9UGB738-285Phosphoinositide dependent signalling – Others2IBN
SNX17Sorting nexin-17, PX domain Q150361-108Phosphoinositide dependent signalling – Others3FOG
IMPA2Inositol monophosphatase 2 O1473216-288Phosphoinositide dependent signalling – PIP-Phosphatases2FVZ
INPP5BType II inositol 1,4,5-trisphosphate 5-phosphatase P32019339-643Phosphoinositide dependent signalling – PIP-Phosphatases3MTC
INPP5BType II inositol 1,4,5-trisphosphate 5-phosphatase P32019341-646Phosphoinositide dependent signalling – PIP-Phosphatases3N9V
INPP5EPhosphatidylinositol polyphosphate 5-phosphatase type IVQ9NRR6275-623Phosphoinositide dependent signalling – PIP-Phosphatases2XSW
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2O15357419-732Phosphoinositide dependent signalling – PIP-Phosphatases3NR8
DNPEPAspartyl aminopeptidase Q9ULA01-478Protease-Other3L6S (4DYO)
G3BP1Ras GTPase-activating protein-binding protein 1, NTF2 domain Q132831-139Receptor Signaling Domains3Q90
SKILSki-like protein P12757137-238Receptor Signaling Domains3EQ5
TLR10Toll-like receptor 10, TIR domain Q9BXR5622-776Receptor Signaling Domains2J67
NUDT21Cleavage and polyadenylation specificity factor subunit 5 O4380921-227RNA processing3N9U
LASP1LIM and SH3 domain protein 1, SH3 domain Q14847202-261SH3 domain3I35
SOCS6Suppressor of cytokine signaling 6, SH2 domain O14544361-499SOCS-box-containing2VIF
SPSB1SPRY domain-containing SOCS box protein 1 Q96BD624-233SOCS-box-containing2JK9
SPSB2SPRY domain-containing SOCS box protein 2 Q9961926-219SOCS-box-containing3EMW
SPSB4SPRY domain-containing SOCS box protein 4 Q96A4428-233SOCS-box-containing2V24
AMPHAmphiphysinP4941834-236To be assigned3SOG
ENO3Beta-enolaseP139291-434To be assigned2XSX
GYG1Glycogenin 1P469761-262To be assigned3Q4S
HBP1HMG-box transcription factor 1O60381206-342To be assigned3QVE
MACROH2A2Core histone macro-H2A.2 Q9P0M6177-369To be assigned2XD7
EBF1Transcription factor COE1, DNA binding domain Q9UH7310-250Transcription-Factor3LYR
EBF1Transcription factor COE1, IPT/TIG domain Q9UH73258-351Transcription-Factor3MQI
EBF3Transcription factor COE3, IPT/TIG domain Q9H4W6261-395Transcription-Factor3MUJ
EBF3Transcription factor COE3, IPT/TIG domain, helix-loop-helix domain Q9H4W6261-415Transcription-Factor3N50
ACAA13-ketoacyl-CoA thiolase, peroxisomalP0911030-424Transferase2IIK
FDPSFarnesyl pyrophosphate synthaseP1432467-419Transferase2QIS
GGPS1Geranylgeranyl pyrophosphate synthaseO957491-300Transferase2Q80
GOT1Aspartate aminotransferase 1, cytoplasmicP1717414-412Transferase3II0
HMGCS1Hydroxymethylglutaryl-CoA synthase, cytoplasmicQ0158116-470Transferase2P8U
HMGCS23-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)Transferase2V4W
MAT1AMethionine adenosyltransferase I, alpha Q0026616-395Transferase2OBV
MAT2AMethionine adenosyltransferase II, alpha P311531-395Transferase2P02
MCATMalonyl-CoA:acyl carrier protein transacylase (malonyltransferase) [isoform 1] Q8IVS260-375Transferase2C2N
OXCT13-oxoacid CoA transferase P5580940-520Transferase3DLX
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial Q9NWU139-459Transferase2C9H
TKTTransketolase P2940110-620Transferase3OOY
TGM1Protein-glutamine gamma-glutamyltransferase K, Ig domain P22735693-787Transglutaminase2XZZ
ARNTAryl hydrocarbon receptor nuclear translocator P27540 356-470Various other targets
BAK1Bcl-2 homologous antagonist/killer, mitochondrial apoptosis regulator Q1661121-190Various other targets2JCN
BCL2A1 Bcl-2-related protein A1 Q165481-149Various other targets2VM6
EPAS1Endothelial PAS domain-containing protein 1 Q99814239-350Various other targets
GLS Glutaminase kidney isoform, mitochondrial O94925221-533Various other targets3CZD
NT5C2Cytosolic purine 5′-nucleotidase P499021-536Various other targets2J2C/2JC9/2JCM
NT5C3Cytosolic 5′-nucleotidase 3A Q9H0P064-336Various other targets2CN1/2JGA/2VKQ
NUDTOxidized purine nucleoside triphosphate hydrolase P3663942-197Various other targets
SYN3Synapsin 3O1499476-417Vesicle-Transport2P0A
ZFYVE16Zinc finger FYVE domain-containing protein 16, FYVE zinc finger domain Q7Z3T8733-820zinc finger domain3T7L
PKM2 Pyruvate kinase isozymes P146183-530

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